Papuloerythroderma of Ofuji is a rare disorder most commonly found in Japan, characterized by pruritic papules that spare the skinfolds, producing bands of uninvolved cutis, creating the so-called deck-chair sign. Frequently there is associated blood eosinophilia. Skin biopsies reveal a dense lymphohistiocytic infiltrate, eosinophils in the papillary dermis, and increased Langerhans cells (S-100 positive). Systemic steroids are the treatment of choice and may result in long-term remissions.[1]: 57 [2]
It was characterized in 1984.[3][4]
Use of PUVA in treatment has been described.[5]
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See also
References
- ^ James WD, Berger TG, Elston DM (2005). Andrews' Diseases of the Skin: Clinical Dermatology (10th ed.). Saunders. p. 56. ISBN 978-0-7216-2921-6.
- ^ Rapini RP, Bolognia JL, Jorizzo JL (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. ISBN 978-1-4160-2999-1.
- ^ Torchia D, Miteva M, Hu S, Cohen C, Romanelli P (March 2010). "Papuloerythroderma 2009: two new cases and systematic review of the worldwide literature 25 years after its identification by Ofuji et al". Dermatology. 220 (4): 311–320. doi:10.1159/000301915. PMID 20339287. S2CID 23915213.
- ^ Ofuji S, Furukawa F, Miyachi Y, Ohno S (1984). "Papuloerythroderma". Dermatologica. 169 (3): 125–130. doi:10.1159/000249586. PMID 6148269.
- ^ Burg G, Kempf W (2005). Cutaneous Lymphomas. Informa Health Care. pp. 365–. ISBN 978-0-8247-2997-4. Retrieved 30 May 2010.
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This page was last edited on 9 December 2022, at 08:55