NRBF2

NRBF2

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
4ZEY

Identifiers

Aliases

NRBF2, COPR1, COPR2, NRBF-2, COPR, nuclear receptor binding factor 2

External IDs

OMIM: 616477; MGI: 1354950; HomoloGene: 41473; GeneCards: NRBF2; OMA:NRBF2 - orthologs

Gene location (Human)

Chr.	Chromosome 10 (human)^[1]

Band	10q21.3	Start	63,133,247 bp^[1]
Band	10q21.3	End	63,155,031 bp^[1]

Gene location (Mouse)

Chr.	Chromosome 10 (mouse)^[2]

Band	10\|10 B5.1	Start	67,102,468 bp^[2]
Band	10\|10 B5.1	End	67,121,084 bp^[2]

RNA expression pattern

Bgee

Human

Mouse (ortholog)

Top expressed in

blood

amniotic fluid

monocyte

Achilles tendon

right lobe of liver

bone marrow

palpebral conjunctiva

islet of Langerhans

stromal cell of endometrium

gastrocnemius muscle

Top expressed in

proximal tubule

quadriceps femoris muscle

neural tube

secondary oocyte

skeletal muscle tissue

liver

white adipose tissue

jejunum

zone of skin

More reference expression data

BioGPS

n/a

Gene ontology
Molecular function	protein binding
Cellular component	cytoplasm phosphatidylinositol 3-kinase complex, class III autophagosome nucleus nucleoplasm cytoplasmic vesicle
Biological process	transcription initiation from RNA polymerase II promoter regulation of transcription, DNA-templated response to endoplasmic reticulum stress transcription, DNA-templated regulation of lipid kinase activity autophagy
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse

Entrez


29982


641340

Ensembl


ENSG00000148572


ENSMUSG00000075000

UniProt


Q96F24


Q8VCQ3

RefSeq (mRNA)


NM_001282405 NM_030759


NM_001036293

RefSeq (protein)


NP_001269334 NP_110386


NP_001031370 NP_001388976 NP_001388977

Location (UCSC)

Chr 10: 63.13 – 63.16 Mb

Chr 10: 67.1 – 67.12 Mb

PubMed search

^[3]

^[4]

Wikidata

View/Edit Human

View/Edit Mouse

Nuclear receptor-binding factor 2 is a protein that in humans is encoded by the NRBF2 gene.^[5]^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000148572 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000075000 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Yasumo H, Masuda N, Furusawa T, Tsukamoto T, Sadano H, Osumi T (May 2000). "Nuclear receptor binding factor-2 (NRBF-2), a possible gene activator protein interacting with nuclear hormone receptors". Biochim Biophys Acta. 1490 (1–2): 189–97. doi:10.1016/S0167-4781(99)00244-4. PMID 10786636.
^ "Entrez Gene: NRBF2 nuclear receptor binding factor 2".

Adams MD, Kerlavage AR, Fleischmann RD, et al. (1995). "Initial assessment of human gene diversity and expression patterns based upon 83 million nucleotides of cDNA sequence" (PDF). Nature. 377 (6547 Suppl): 3–174. PMID 7566098.
Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Flores AM, Li L, Aneskievich BJ (2005). "Isolation and functional analysis of a keratinocyte-derived, ligand-regulated nuclear receptor comodulator". J. Invest. Dermatol. 123 (6): 1092–101. doi:10.1111/j.0022-202X.2004.23424.x. PMID 15610520.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.

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2crb: Solution structure of MIT domain from mouse NRBF-2

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This page was last edited on 17 October 2022, at 15:15

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