To install click the Add extension button. That's it.

The source code for the WIKI 2 extension is being checked by specialists of the Mozilla Foundation, Google, and Apple. You could also do it yourself at any point in time.

4,5
Kelly Slayton
Congratulations on this excellent venture… what a great idea!
Alexander Grigorievskiy
I use WIKI 2 every day and almost forgot how the original Wikipedia looks like.
Live Statistics
English Articles
Improved in 24 Hours
Added in 24 Hours
What we do. Every page goes through several hundred of perfecting techniques; in live mode. Quite the same Wikipedia. Just better.
.
Leo
Newton
Brights
Milds

Mycobacterium avium complex

From Wikipedia, the free encyclopedia

Mycobacterium avium complex
Scientific classification
Domain:
Phylum:
Class:
Order:
Family:
Genus:
Species complex:
Mycobacterium avium complex
Binomial name
Mycobacterium intracellulare
Runyon 1965,[1] ATCC 13950
Mycobacterium avium
Chester 1901 emend. Thorel et al. 1990

Mycobacterium avium complex is a group of mycobacteria comprising Mycobacterium intracellulare and Mycobacterium avium that are commonly grouped because they infect humans together; this group, in turn, is part of the group of nontuberculous mycobacteria. These bacteria cause Mycobacterium avium-intracellulare infections or Mycobacterium avium complex infections in humans.[2] These bacteria are common and are found in fresh and salt water, in household dust and in soil.[3] MAC bacteria usually cause infection in those who are immunocompromised or those with severe lung disease.

YouTube Encyclopedic

  • 1/5
    Views:
    29 712
    15 285
    1 272
    655
    1 885
  • Mycobacterium avium complex - causes, symptoms, diagnosis, treatment, pathology
  • Mycobacterium avium complex (MAC)
  • Mycobacterium Avium Complex (Mnemonic for the USMLE)
  • Mycobacterium avium-intracellulare, scrofulaceum and marinum for the USMLE Step 1
  • The Changing Face of Nontuberculous Mycobacterial (NTM) Disease: Lady Windermere shares the Stage

Transcription

Description

Slant tubes of Löwenstein-Jensen medium. From left to right:
- Negative control
- M. tuberculosis: Dry-appearing colonies
- Mycobacterium avium complex: Wet-appearing colonies
- M. gordonae: Yellowish colonies

In the Runyon classification, both bacteria are nonchromogens. They can be differentiated from M. tuberculosis and each other by commercially available DNA probes.[4]: 245 

They are characterized as Gram-positive, nonmotile, acid-fast, short to long rods.[citation needed]

Colony characteristics

  • Usually, colonies are smooth, rarely rough, and not pigmented colonies. Older colonies may become yellow.

Physiology

Differential characteristics

  • M. intracellulare and M. avium form the M. avium complex (MAC).
  • Remarkable ITS heterogeneity is seen within different M. intracellulare isolates.

Species

Type strains

  • M. intracellulare type strains include ATCC 13950, CCUG 28005, CIP 104243, DSM 43223, JCM 6384, and NCTC 13025.[6]
  • M. avium type strains include ATCC 25291, DSM 44156, and TMC 724.[7]

Human health

MAC bacteria enter most people's body when inhaled into the lungs or swallowed, but only cause infection in those who are immunocompromised or who have severe lung disease such as those with cystic fibrosis or chronic obstructive lung disease (COPD).[3] MAC infection can cause COPD and lymphadenitis, and can cause disseminated disease, especially in people with immunodeficiency.[4]: 245  During the last decade Mycobacterium chimaera (see below) infections following cardiothoracic surgery, especially open-heart surgery, have been increasingly reported worldwide.[8] Infections usually involve the respiratory system. Mycobacterium chimaera is acquired during cardiopulmonary bypass via bioaerosols emitted from contaminated heater-cooler units water systems. Due to nonspecific symptoms and long latency, postoperative Mycobacterium chimaera infections may not be promptly diagnosed and treated, and may become life-threatening.

History

In 2004, Tortoli et al. proposed the name M. chimaera for strains that a reverse hybridization–based line probe assay suggested belonged to MAIS (M. avium–M. intracellulare–M. scrofulaceum group), but were different from M. avium, M. intracellulare, or M. scrofulaceum. The new species name comes from the Chimera, a mythological being made up of parts of three different animals.[9][10]

References

  1. ^ Runyon, E. 1965. Pathogenic mycobacteria. Advances in Tuberculosis Research, 14, 235-287.
  2. ^ "Mycobacterium Avium Complex. MAI; MAC Information". Patient Info. 29 August 2014.
  3. ^ a b "Mycobacterium Avium Complex infections | Genetic and Rare Diseases Information Center (GARD) – an NCATS Program". rarediseases.info.nih.gov. Retrieved 2020-03-29.
  4. ^ a b Jones-Lopez, Edward C.; Ellner, Jerrold J. (2011). "Chapter 35: Tuberculosis and Atypical Mycobacterial Infections". In Guerrant, Richard L.; Walker, David H.; Weller, Peter F. (eds.). Tropical infectious diseases : principles, pathogens, & practice (3rd ed.). Edinburgh: Saunders. ISBN 9780702039355.
  5. ^ Haworth CS, Banks J, Capstick T, Fisher AJ, Gorsuch T, Laurenson IF, Leitch A, Loebinger MR, Milburn HJ, Nightingale M, Ormerod P, Shingadia D, Smith D, Whitehead N, Wilson R, Floto RA (November 2017). "British Thoracic Society guidelines for the management of non-tuberculous mycobacterial pulmonary disease (NTM-PD)". Thorax. 72 (Suppl 2): ii1–ii64. doi:10.1136/thoraxjnl-2017-210927. PMID 29054853.
  6. ^ Type strain of Mycobacterium intracellulare at BacDive -  the Bacterial Diversity Metadatabase
  7. ^ Type strain of Mycobacterium avium at BacDive -  the Bacterial Diversity Metadatabase
  8. ^ Riccardi, Niccolò; Monticelli, Jacopo; Antonello, Roberta Maria; Luzzati, Roberto; Gabrielli, Marco; Ferrarese, Maurizio; Codecasa, Luigi; Di Bella, Stefano; Giacobbe, Daniele Roberto (2020). "Mycobacterium chimaera infections: An update". Journal of Infection and Chemotherapy. 26 (3): 199–205. doi:10.1016/j.jiac.2019.11.004.
  9. ^ Henry, Ronnie (March 2017). "Etymologia: Mycobacterium chimaera". Emerg Infect Dis. 23 (3): 499. doi:10.3201/eid2303.ET2303. PMC 5382748. Citing public domain text from the CDC.
  10. ^ Tortoli, E; Rindi, L; Garcia, MJ; Chiaradonna, P; Dei, R; Garzelli, C; Kroppenstedt, RM; Lari, N; Mattei, R; Mariottini, A; Mazzarelli, G; Murcia, MI; Nanetti, A; Piccoli, P; Scarparo, C (July 2004). "Proposal to elevate the genetic variant MAC-A, included in the Mycobacterium avium complex, to species rank as Mycobacterium chimaera sp. nov". International Journal of Systematic and Evolutionary Microbiology. 54 (Pt 4): 1277–85. doi:10.1099/ijs.0.02777-0. PMID 15280303.

External links

This page was last edited on 2 February 2024, at 17:58
Basis of this page is in Wikipedia. Text is available under the CC BY-SA 3.0 Unported License. Non-text media are available under their specified licenses. Wikipedia® is a registered trademark of the Wikimedia Foundation, Inc. WIKI 2 is an independent company and has no affiliation with Wikimedia Foundation.