Monitored Emergency Use of Unregistered and Investigational Interventions (MEURI) is an ethical protocol developed by the World Health Organization to evaluate the potential use of experimental drugs in the event of public health emergencies.[1][2] The protocol was created by the WHO Ebola Ethics Working Group in 2014[3][4] in the context of the 2014 West Africa Ebola outbreak. The WHO recommends that the term be preferred to the term "compassionate use" or "expanded access" for the controlled use of unregistered treatments in public health emergency measures.[5][6]
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References
- ^ World Health Organization (WHO). (2016). Emergency use of unproven interventions outside of research [Chapter 9]. In Guidance for Managing Ethical Issues in Infectious Disease Outbreaks. World Health Organization. https://apps.who.int/iris/handle/10665/250580. alternative DOI: https://doi.org/10.5281/zenodo.3715302
- ^ "Notes for the record: Consultation on Monitored Emergency Use of Unregistered and Investigational Interventions for Ebola Virus Disease (EVD)" (PDF). World Health Organization. 17 May 2018. Retrieved 26 May 2018.
- ^ WHO Ethics Working Group (2014). "Ethical issues related to study design for trials on therapeutics for Ebola Virus Disease: WHO Ethics Working Group meeting 20–21 October, summary of discussion". World Health Organization. hdl:10665/137509.
{{cite journal}}: Cite journal requires|journal=(help) - ^ Calain, Philippe (2018-01-01). "The Ebola clinical trials: a precedent for research ethics in disasters". Journal of Medical Ethics. 44 (1): 3–8. doi:10.1136/medethics-2016-103474. ISSN 0306-6800. PMC 5749307. PMID 27573153.
- ^ Richardson, Thomas; Johnston, Andrew McDonald; Draper, Heather (2017-01-17). "A Systematic Review of Ebola Treatment Trials to Assess the Extent to Which They Adhere to Ethical Guidelines". PLOS ONE. 12 (1): e0168975. Bibcode:2017PLoSO..1268975R. doi:10.1371/journal.pone.0168975. PMC 5240928. PMID 28095476.
- ^ Alirol, Emilie; Kuesel, Annette C.; Guraiib, Maria Magdalena; dela Fuente-Núñez, Vânia; Saxena, Abha; Gomes, Melba F. (2017-06-26). "Ethics review of studies during public health emergencies - the experience of the WHO ethics review committee during the Ebola virus disease epidemic". BMC Medical Ethics. 18 (1): 43. doi:10.1186/s12910-017-0201-1. ISSN 1472-6939. PMC 5485606. PMID 28651650.
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This page was last edited on 4 November 2023, at 22:57