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Methyldihydromorphine

From Wikipedia, the free encyclopedia

Methyldihydromorphine
Clinical data
ATC code
  • none
Legal status
Legal status
Identifiers
  • (5α,6α)-6,17-Dimethyl-4,5-epoxymorphinan-3,6-diol
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC18H23NO3
Molar mass301.386 g·mol−1
3D model (JSmol)
  • C[C@@]1(CC[C@H]2[C@H]3Cc4ccc(c5c4[C@]2([C@H]1O5)CCN3C)O)O
  • InChI=1S/C18H23NO3/c1-17(21)6-5-11-12-9-10-3-4-13(20)15-14(10)18(11,16(17)22-15)7-8-19(12)2/h3-4,11-12,16,20-21H,5-9H2,1-2H3/t11-,12+,16-,17-,18-/m0/s1 ☒N
  • Key:NBKVWIJQJMEQLE-NGTWOADLSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

Methyldihydromorphine[2] is a semi-synthetic opioid originally developed in Germany in 1936, controlled under both domestic law and UN conventions because of its possible potential for abuse. Methyldihydromorphine is related to heterocodeine and is not a synonym for dihydrocodeine or dihydroheterocodeine (6-methoxydihydromorphine).

This compound is a derivative of hydromorphone[3] It has been found to be 33 percent the analgesic potency of morphine with a substantially longer duration of action.[3]

So far, little is currently known about this compound. It is a Schedule I controlled substance in the United States with an ACSCN of 9304 and a 2013 annual manufacturing quota of 2 grams.[4]

References

  1. ^ Anvisa (2023-03-31). "RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" [Collegiate Board Resolution No. 784 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (in Brazilian Portuguese). Diário Oficial da União (published 2023-04-04). Archived from the original on 2023-08-03. Retrieved 2023-08-16.
  2. ^ U.S. Patent 2,104,058
  3. ^ a b Reynolds AK, Randall LO (1957). Morphine & Allied Drugs. Toronto: University of Toronto Press. p. 194.
  4. ^ "Quotas - 2013". Drug Enforcement Administration. United States Department of Justice.



This page was last edited on 6 October 2023, at 07:22
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