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Macavirus

From Wikipedia, the free encyclopedia

Macavirus
Virus classification Edit this classification
(unranked): Virus
Realm: Duplodnaviria
Kingdom: Heunggongvirae
Phylum: Peploviricota
Class: Herviviricetes
Order: Herpesvirales
Family: Orthoherpesviridae
Subfamily: Gammaherpesvirinae
Genus: Macavirus
Species

See text

Macavirus is a genus of viruses in the order Herpesvirales, in the family Herpesviridae, in the subfamily Gammaherpesvirinae. Mammals serve as natural hosts. There are nine species in this genus. Diseases associated with this genus include: inapparent infection in their reservoir hosts (wildebeest for alHV-1 and sheep for ovHV-2), but fatal lymphoproliferative disease when they infect MCF-susceptible hosts, including cattle, deer, bison, water buffalo and pigs.[1][2]

Species

The genus consists of the following nine species:[2]

Structure

Viruses in Macavirus are enveloped, with icosahedral, spherical to pleomorphic, and Round geometries, and T=16 symmetry. The diameter is around 150-200 nm. Genomes are linear and non-segmented, around 180kb in length.[1]

Genus Structure Symmetry Capsid Genomic arrangement Genomic segmentation
Macavirus Spherical pleomorphic T=16 Enveloped Linear Monopartite

Life cycle

Viral replication is nuclear, and is lysogenic. Entry into the host cell is achieved by attachment of the viral glycoproteins to host receptors, which mediates endocytosis. Replication follows the dsDNA bidirectional replication model. Dna templated transcription, with some alternative splicing mechanism is the method of transcription. The virus exits the host cell by nuclear egress, and budding. Mammals serve as the natural host.[1]

Genus Host details Tissue tropism Entry details Release details Replication site Assembly site Transmission
Macavirus Mammals B-lymphocytes Glycoprotiens Budding Nucleus Nucleus Sex; saliva

References

  1. ^ a b c "Viral Zone". ExPASy. Retrieved 15 June 2015.
  2. ^ a b "Virus Taxonomy: 2020 Release". International Committee on Taxonomy of Viruses (ICTV). March 2021. Retrieved 10 May 2021.

External links

Wikimedia Commons has media related to Macavirus.
Wikispecies has information related to Macavirus.
This page was last edited on 30 January 2023, at 12:42
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