Magnesium transporter protein 1

MAGT1

Identifiers

MAGT1, IAP, MRX95, OST3B, PRO0756, XMEN, bA217H1.1, RP11-217H1.1, magnesium transporter 1, SLC58A1, CDG1CC

External IDs

OMIM: 300715 MGI: 1914325 HomoloGene: 100678 GeneCards: MAGT1

Gene location (Human)

Chr.	X chromosome (human)^[1]

Band	Xq21.1	Start	77,825,747 bp^[1]
Band	Xq21.1	End	77,899,271 bp^[1]

Gene location (Mouse)

Chr.	X chromosome (mouse)^[2]

Band	X\|X D	Start	105,011,690 bp^[2]
Band	X\|X D	End	105,055,512 bp^[2]

RNA expression pattern

Bgee

Human

Mouse (ortholog)

Top expressed in

palpebral conjunctiva

corpus epididymis

tibia

parotid gland

germinal epithelium

pericardium

visceral pleura

parietal pleura

seminal vesicula

jejunal mucosa

Top expressed in

parotid gland

lacrimal gland

ciliary body

seminal vesicula

Paneth cell

submandibular gland

islet of Langerhans

iris

epithelium of stomach

sciatic nerve

More reference expression data

BioGPS


More reference expression data

Gene ontology
Molecular function	magnesium ion transmembrane transporter activity dolichyl-diphosphooligosaccharide-protein glycotransferase activity
Cellular component	integral component of membrane oligosaccharyltransferase complex plasma membrane integral component of plasma membrane membrane endoplasmic reticulum membrane azurophil granule membrane endoplasmic reticulum
Biological process	magnesium ion transport protein N-linked glycosylation cognition transmembrane transport magnesium ion transmembrane transport neutrophil degranulation protein glycosylation protein N-linked glycosylation via asparagine transport
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse

Entrez


84061


67075

Ensembl


ENSG00000102158


ENSMUSG00000031232

UniProt


Q9H0U3


Q9CQY5

RefSeq (mRNA)


NM_032121 NM_001367916


NM_001190409 NM_025952 NM_001377002 NM_001377003

RefSeq (protein)


NP_115497 NP_001354845


NP_001177338 NP_080228 NP_001363931 NP_001363932

Location (UCSC)

Chr X: 77.83 – 77.9 Mb

Chr X: 105.01 – 105.06 Mb

PubMed search

^[3]

^[4]

Wikidata

View/Edit Human

View/Edit Mouse

Magnesium transporter protein 1 is a protein that in humans is encoded by the MAGT1 gene.^[5]^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000102158 - Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000031232 - Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Goytain A, Quamme GA (May 2005). "Identification and characterization of a novel mammalian Mg2+ transporter with channel-like properties". BMC Genomics. 6 (1): 48. doi:10.1186/1471-2164-6-48. PMC 1129089. PMID 15804357.
^ "MAGT1 magnesium transporter 1 [ Homo sapiens (human) ]".

Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
Yu Y, Zhang C, Zhou G, et al. (2001). "Gene Expression Profiling in Human Fetal Liver and Identification of Tissue- and Developmental-Stage-Specific Genes through Compiled Expression Profiles and Efficient Cloning of Full-Length cDNAs". Genome Res. 11 (8): 1392–403. doi:10.1101/gr.175501. PMC 311073. PMID 11483580.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Kelleher DJ, Karaoglu D, Mandon EC, Gilmore R (2003). "Oligosaccharyltransferase isoforms that contain different catalytic STT3 subunits have distinct enzymatic properties". Mol. Cell. 12 (1): 101–11. doi:10.1016/S1097-2765(03)00243-0. PMID 12887896.
Clark HF, Gurney AL, Abaya E, et al. (2003). "The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Deloukas P, Earthrowl ME, Grafham DV, et al. (2004). "The DNA sequence and comparative analysis of human chromosome 10". Nature. 429 (6990): 375–81. Bibcode:2004Natur.429..375D. doi:10.1038/nature02462. PMID 15164054.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Shibatani T, David LL, McCormack AL, et al. (2005). "Proteomic analysis of mammalian oligosaccharyltransferase reveals multiple subcomplexes that contain Sec61, TRAP, and two potential new subunits". Biochemistry. 44 (16): 5982–92. doi:10.1021/bi047328f. PMID 15835887.
Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries". DNA Res. 12 (2): 117–26. doi:10.1093/dnares/12.2.117. PMID 16303743.

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This page was last edited on 3 December 2023, at 00:00

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See also

References

Further reading