To install click the Add extension button. That's it.

The source code for the WIKI 2 extension is being checked by specialists of the Mozilla Foundation, Google, and Apple. You could also do it yourself at any point in time.

How to transfigure the Wikipedia

Would you like Wikipedia to always look as professional and up-to-date? We have created a browser extension. It will enhance any encyclopedic page you visit with the magic of the WIKI 2 technology.

Try it — you can delete it anytime.

Install in 5 seconds
4,5
Kelly Slayton
Congratulations on this excellent venture… what a great idea!
Alexander Grigorievskiy
I use WIKI 2 every day and almost forgot how the original Wikipedia looks like.
Live Statistics
English Articles
Improved in 24 Hours
Added in 24 Hours
Languages
Recent
Show all languages
What we do. Every page goes through several hundred of perfecting techniques; in live mode. Quite the same Wikipedia. Just better.
Great Wikipedia has got greater.
.
Leo
Newton
Brights
Milds

Lipegfilgrastim

From Wikipedia, the free encyclopedia

Lipegfilgrastim
Clinical data
Trade namesLonquex
Other namesXM-22
AHFS/Drugs.comUK Drug Information
Routes of
administration		Subcutaneous injection
Drug classImmunostimulants, colony-stimulating factors[1]
ATC code
Legal status
Legal status
  • AU: S4 (Prescription only)[2]
  • UK: POM (Prescription only)[3]
  • EU: Rx-only
Pharmacokinetic data
MetabolismSaturable proteolytic enzymes (not cytochrome P450 system mediated)[4]
Elimination half-life32–62 hours[4]
Identifiers
CAS Number
PubChem CID
DrugBank
UNII
KEGG
ChEMBL
Chemical and physical data
FormulaC866H1372N226O258S9 + PEG
Molar mass39000 g·mol−1

Lipegfilgrastim, sold under the brand name Lonquex, is a medication used to reduce the duration of neutropenia and the incidence of febrile neutropenia in adults.[1] It is given by injection under the skin in the abdomen, upper arm or thigh.[1]

The most common side effects include nausea as well as bone and muscle pain.[1]

Lipegfilgrastim is similar to granulocyte colony stimulating factor (G‑CSF), a naturally occurring protein in the body that stimulates the production of white blood cells including neutrophils in the bone marrow.[1] Lipegfilgrastim acts in the same way as G‑CSF, increasing the production of neutrophils and thereby helping to reduce the duration of neutropenia and the occurrence of febrile neutropenia (a sign of infection) in people receiving chemotherapy.[1]

Lipegfilgrastim is a filgrastim biosimilar.[1] In lipegfilgrastim, the filgrastim has been 'pegylated' (attached to polyethylene glycol).[1] This slows down the medicine's removal from the body and allows the medicine to be given less often.[1]

Lipegfilgrastim was authorized for medical use in the European Union in July 2013.[1]

YouTube Encyclopedic

  • 1/5
    Views:
    2 256
    433
    7 660
    446
    36 565
  • Lonquex (Lipegfilgrastim) Injection
  • Pegfilgrastim versus filgrastim for supportive care of heavily pretreated multiple myeloma
  • How to Use the Australian Injectable Drugs Handbook, Eighth Edition (AIDH8)
  • A nasty surprise
  • Module Injecteren - Subcutaan injecteren loodrechttechniek | Zorg-Wijs

Transcription

Medical uses

Lipegfilgrastim is indicated for the reduction in the duration of neutropenia and the incidence of febrile neutropenia in adults treated with cytotoxic chemotherapy for malignancy (with the exception of chronic myeloid leukaemia and myelodysplastic syndromes).[1]

References

  1. ^ a b c d e f g h i j k "Lonquex EPAR". European Medicines Agency. 17 September 2018. Retrieved 13 July 2020. Text was copied from this source which is © European Medicines Agency. Reproduction is authorized provided the source is acknowledged.
  2. ^ "Prescription medicines: registration of new chemical entities in Australia, 2015". Therapeutic Goods Administration (TGA). 21 June 2022. Retrieved 10 April 2023.
  3. ^ "Lonquex - Summary of Product Characteristics (SmPC)". (emc). 3 September 2019. Retrieved 12 July 2020.
  4. ^ a b Hoggatt, J; Tate, TA; Pelus, LM (2015). "Role of lipegfilgrastim in the management of chemotherapy-induced neutropenia". International Journal of Nanomedicine. 10: 2647–52. doi:10.2147/IJN.S55796. PMC 4388090. PMID 25878498.

Further reading


Stub icon

This antineoplastic or immunomodulatory drug article is a stub. You can help Wikipedia by expanding it.

This page was last edited on 15 March 2024, at 00:21
Basis of this page is in Wikipedia. Text is available under the CC BY-SA 3.0 Unported License. Non-text media are available under their specified licenses. Wikipedia® is a registered trademark of the Wikimedia Foundation, Inc. WIKI 2 is an independent company and has no affiliation with Wikimedia Foundation.
Contact WIKI 2
Introduction
Terms of Service
Privacy Policy