To install click the Add extension button. That's it.

The source code for the WIKI 2 extension is being checked by specialists of the Mozilla Foundation, Google, and Apple. You could also do it yourself at any point in time.

4,5
Kelly Slayton
Congratulations on this excellent venture… what a great idea!
Alexander Grigorievskiy
I use WIKI 2 every day and almost forgot how the original Wikipedia looks like.
Live Statistics
English Articles
Improved in 24 Hours
Added in 24 Hours
What we do. Every page goes through several hundred of perfecting techniques; in live mode. Quite the same Wikipedia. Just better.
.
Leo
Newton
Brights
Milds

From Wikipedia, the free encyclopedia

Invitrogen
TypeSubsidiary
SuccessorLife Technologies Edit this on Wikidata
HeadquartersWaltham, Massachusetts, USA
Key people
Marc N. Casper (President & CEO)
ParentThermo Fisher Scientific

Invitrogen is one of several brands under the Thermo Fisher Scientific corporation. The product line includes various subbrands of biotechnology products, such as machines and consumables for polymerase chain reaction, reverse transcription, cloning, culturing, stem cell production, cell therapy, regenerative medicine, immunotherapy, transfection, DNA/RNA purification, diagnostic tests, antibodies, and immunoassays.

The predecessor corporation was Invitrogen Corporation (formerly traded as NasdaqIVGN), headquartered in Carlsbad, California. In 2008, a merger between Applied Biosystems and Invitrogen[1] was finalized, creating Life Technologies. The latter was acquired by Thermo Fisher Scientific in 2014.

YouTube Encyclopedic

  • 1/3
    Views:
    35 088
    11 964
    6 119
  • How To Run the Bolt Pre-Cast Protein Gel
  • Review 2: Invitrogen Bac-to-Bac expression system
  • Bolt Gel Tank Animation Video

Transcription

History

Founding

Invitrogen was founded in 1987 by Lyle Turner, Joe Fernandez, and William McConnell and was incorporated in 1989. The company initially found success with its kits for molecular cloning—notably, The Librarian, a kit for making cDNA libraries, and the FastTrack Kit for mRNA isolation from biological samples.

William McConnell left the company in 1989.

In 1999, the company, which had reached sales of $33 million the prior year, went public, with a plan of consolidating biotechnology research boutique suppliers. The company had become quite successful at licensing technologies into its niche market, of cloning and expression, but determined that many niche leaders were not interested in licensing, and M&A needed to be added to the company's set of tools for growth.

Mergers and acquisitions

Invitrogen acquired NOVEX, in cloned protein characterization, within 60 days of going public. In December 1999, it purchased Research Genetics, Inc.,[2] a leader in genomics and synthetic DNA chemistry, becoming a $100 million (annual sales) company within a year of its IPO.

The business scope expanded significantly when it acquired the rival biotechnology and cell culture company Life Technologies in 2000; Life had been formed in 1983 when GIBCO (Grand Island Biological Company) which had been founded around 1960 in New York, merged with a reagent company called Bethesda Research Laboratories. The company continued to add technologies through a series of mergers and acquisitions, which broadened its customer base and strengthened its intellectual property portfolio. Among these, established companies such as Ethrog Biotechnology, Molecular Probes (fluorescence-based detection), Dynal (magnetic bead–based separation), Panvera (proteins and assays for drug screening), InforMax (software for computational biology and bioinformatics), BioSource (cellular pathway analysis), CellzDirect (cell products and services for research) and Zymed and Caltag Laboratories (primary and secondary antibodies) have been brought under the Invitrogen brand.[3] Invitrogen acquired Sequitur in 2003 to obtain Sequitur's proprietary Stealth(TM) RNAi technology.

In 2008, Invitrogen virtually doubled its size with the purchase of biotech instrumentation company Applied Biosystems, maker of DNA sequencing and PCR machines and reagents. The company then renamed the overall organization as Life Technologies. The Invitrogen brand and most of the brands acquired still exist on product packaging, although the overall company is called Life Technologies. In summer 2010, the company acquired the computer chip DNA sequencing company Ion Torrent Systems. Through this history of acquisitions and continued product research and development, Invitrogen / Life Technologies had over 50,000 products.

Portfolio

Key products and technologies

Utilizing this business strategy, Invitrogen represented a large number of products: Dynabeads magnetic separation technology, GIBCO cell culture media and reagents, SuperScript reverse transcriptase, Platinum Taq polymerase, TOPO cloning and expression products, Novex protein electrophoresis products, and numerous fluorescent reagents such as Qdot nanocrystals, Alexa Fluor, DyLight, RiboGreen and SYBR dyes. Invitrogen currently offers more than 25,000 products and services to support research in cellular analysis, genomics, proteomics, and drug discovery, and seeks to address research problems in developing fields, including biodefense and environmental diagnostics, bioinformatics, epigenetics, and stem cell research.

Innovation and impact

Under a contract from the Defense Threat Reduction Agency (DTRA), the company developed a prototype hand-held pathogen detection system for the detection of multiple toxins such as ricin, staphylococcal enterotoxin, and botulinum toxin, as well as bacteria that cause anthrax, plague, and other diseases, in a single sample.[4] Invitrogen was also awarded a contract to provide kits for detecting possible E. coli O157 contamination in food at the 2008 Summer Olympcics in Beijing, China.[citation needed] The monitoring program, based on World Health Organization food standards, is conducted by the Beijing Centers for Disease Control and Prevention (CDC) and the Olympic Food Safety program. Similarly, the company's PathAlert technology was selected to monitor Yersinia pestis, the causative agent of the plague, at the Torino Winter Games in 2006. Their Qubit platform for RNA, DNA, and protein quantitation was awarded an R&D 100 Award as being a "Top 100 Technologically Significant New Product" by R&D Magazine.[5]

Invitrogen developed and introduced stem cell products. Among more than 1,200 products for stem cell research, the company offered an engineered stem cell line (BG01v/hOG) and various STEMPRO products for manual passaging of human embryonic stem cells (hESC), to promote hESC growth and expansion, and to allow scientists to ascertain hESC pluripotency.[6]

References

  1. ^ "Invitrogen News". Archived from the original on 2008-12-27. Retrieved 2009-08-05..
  2. ^ News, Bloomberg (December 9, 1999). "Company News; Invitrogen to Acquire Research Genetics". The New York Times. {{cite news}}: |last1= has generic name (help)
  3. ^ "Life Technologies: A Look Back". Genetic Engineering News. April 15, 2013.
  4. ^ Invitrogen Delivers Prototype Handheld Biothreat Detector [1].[dead link]
  5. ^ Invitrogen's Qubit Platform Wins 2007 R&D 100 Award [2].[dead link]
  6. ^ Global Biotech Universe in One Place
This page was last edited on 15 September 2022, at 19:57
Basis of this page is in Wikipedia. Text is available under the CC BY-SA 3.0 Unported License. Non-text media are available under their specified licenses. Wikipedia® is a registered trademark of the Wikimedia Foundation, Inc. WIKI 2 is an independent company and has no affiliation with Wikimedia Foundation.