To install click the Add extension button. That's it.

The source code for the WIKI 2 extension is being checked by specialists of the Mozilla Foundation, Google, and Apple. You could also do it yourself at any point in time.

4,5
Kelly Slayton
Congratulations on this excellent venture… what a great idea!
Alexander Grigorievskiy
I use WIKI 2 every day and almost forgot how the original Wikipedia looks like.
What we do. Every page goes through several hundred of perfecting techniques; in live mode. Quite the same Wikipedia. Just better.
.
Leo
Newton
Brights
Milds

Hypodermic needle

From Wikipedia, the free encyclopedia

Different bevels on hypodermic needles
Syringe on left, hypodermic needle with attached colour coded Luer-Lock connector on right
Hypodermic needle features

A hypodermic needle (from Greek ὑπο- (hypo- = under), and δέρμα (derma = skin)), one of a category of medical tools which enter the skin, called sharps,[1] is a very thin, hollow tube with one sharp tip. It is commonly used with a syringe, a hand-operated device with a plunger, to inject substances into the body (e.g., saline solution, solutions containing various drugs or liquid medicines) or extract fluids from the body (e.g., blood). Large-bore hypodermic intervention is especially useful in catastrophic blood loss or treating shock.

A hypodermic needle is used for rapid delivery of liquids, or when the injected substance cannot be ingested, either because it would not be absorbed (as with insulin), or because it would harm the liver. It is also useful to deliver certain medications that cannot be delivered orally due to vomiting. There are many possible routes for an injection, with intramuscular (into a muscle) and intravenous (into a vein) being the most common. A hypodermic syringe has the ability to retain liquid and blood in it up to years after the last use and a great deal of caution should be taken to use a new syringe every time.

The hypodermic needle also serves an important role in research environments where sterile conditions are required. The hypodermic needle significantly reduces contamination during inoculation of a sterile substrate. The hypodermic needle reduces contamination for two reasons: First, its surface is extremely smooth, which prevents airborne pathogens from becoming trapped between irregularities on the needle's surface, which would subsequently be transferred into the media (e.g. agar) as contaminants; second, the needle's surface is extremely sharp, which significantly reduces the diameter of the hole remaining after puncturing the membrane and consequently prevents microbes larger than this hole from contaminating the substrate.[2][3][4][5]

YouTube Encyclopedic

  • 1/5
    Views:
    265 270
    1 626 897
    40 174
    58 755
    29 297
  • The Hypodermic Needle Theory | Media in Minutes | Episode 1
  • What happens when the injection needle touches bone
  • How It's Made Hypodermic Needles
  • What Needle Should I Use for TRT? (Testosterone Replacement Therapy)
  • Hypodermic Needle Theory: Media Theories

Transcription

Welcome to Media in Minutes' where I talk you through important concepts in media and communication. Today we're talking about the Hypodermic Needle Theory which was one of the earliest ways of thinking about how the mass media influences audiences. It was developed in the 1920s and 1930s after researchers observed the effect of propaganda during World War I and events like the Orson Welles 'War of the Worlds' broadcast. The hypodermic needle theory is a linear communication theory which suggests that media messages are injected directly into the brains of a passive audience. It suggests that we're all the same and we all respond to media messages in the same way. This way of thinking about communication and media influences is no longer really accepted. In the 1930s many researchers realized the limitations of this idea and some dispute with early media theorists gave the idea any serious attention at all. Nevertheless, the Hypodermic Needle Theory continues to influence the way we talk about the media. People believe that the mass media has a powerful effect. Parents worry about the influence of television in violent video games. News outlets run headlines like 'Is Google making a stupid?' and 'Grand Theft Auto led teen to kill.' So how did this way of thinking about the mass media develop? Back in 1927, Harold Lasswell an American political scientist and communication theorist published a book called 'Propaganda Technique in the World War' Writing about the effect of Allied propaganda during World War I, Lasswell wrote: "From a propaganda point-of-view it was matchless performance for Wilson brewed the subtle poison which industrious men injected into the veins of a staggering people until the smashing powers of the Allied armies knocked them into submission." The Payne Fund Studies which were conducted between 1929 and 1932 and looked at the effect movies have on children also contributed to this idea that the mass media has a powerful and direct influence on the audiences. Although these studies have been criticized for the lack of scientific rigour, they were really one of the first and most comprehensive examinations of how the media works Writing about the influence of movies the project chairman W.W Charters wrote that they have the potential to profoundly affect the way children behave. Even in the 1930s, however, researches were starting to realize that this way of thinking about media influence was kind of inadequate. Then, in 1938 Orson Welles and the Mercury Theatre broadcast a dramatisation of HG Wells' 'War of the Worlds.' Ladies and gentlemen, I have a grave announcement to make. Incredible as it may seem, both the observations of science and the evidence of our eyes lead to the inescapable assumption that those strange beings who landed in the Jersey farmlands tonight of the vanguard of an invading army from the planet Mars. The battle which took place tonight at Grovers Mill has ended in one of the most startling military defeats ever suffered by an army in modern times; seven thousand men armed with rifles and machine guns pitted against a single fighting machine of the invaders from Mars. One hundred and twenty known survivors. The rest strewn over the battle area from Grovers Mill to Plainsboro crushed and trampled to death under the metal feet of the monster, or burned to cinders by its heat ray. The program, which was presented in the format of a news bulletin, caused some listeners to believe that the Earth was being invited by martians. The New York Times claimed that thousands of people were gripped by mass hysteria. While thousands of people may have been panic-stricken, they were only a small proportion of the six million people who enjoy a quiet night around the radio. On the surface, events like they seem to suggest that the media can have a powerful influence on audiences. Nevertheless, The Hypodermic Needle Theory is kind of inadequate to describe the process of communication immediate influence It just doesn't work.

History

Early use and experimentation

The ancient Greeks and Romans knew injection as a method of medicinal delivery from observations of snakebites and poisoned weapons.[6] There are also references to "anointing" and "inunction" in the Old Testament as well as the works of Homer, but injection as a legitimate medical tool was not truly explored until the 17th century.[7]

Christopher Wren performed the earliest confirmed experiments with crude hypodermic needles, performing intravenous injection into dogs in 1656.[7] These experiments consisted of using animal bladders (as the syringe) and goose quills (as the needle) to administer drugs such as opium intravenously to dogs. Wren and others' main interest was to learn if medicines traditionally administered orally would be effective intravenously. In the 1660s, Johann Daniel Major of Kiel and Johann Sigismund Elsholtz of Berlin were the first to experiment with injections in humans.[6][8] These early experiments were generally ineffective and in some cases fatal. Injection fell out of favor for two centuries.

19th-century development

Syringe made entirely of glass, similar to the Wood design, except it is etched with volume marks.

The 19th century saw the development of medicines that were effective in small doses, such as opiates and strychnine. This spurred a renewed interest in direct, controlled application of medicine. "Some controversy surrounds the question of priority in hypodermic medication."[9] Irish physician Francis Rynd is generally credited with the first successful injection in 1844, in the Meath Hospital in Dublin, Ireland.[10][11]

Alexander Wood's main contribution was the all-glass syringe in 1851, which allowed the user to estimate dosage based on the levels of liquid observed through the glass.[12] Wood used hypodermic needles and syringes primarily for the application of localized, subcutaneous injection (localized anesthesia) and therefore was not as interested in precise dosages.[8]

Simultaneous to Wood's work in Edinburgh, Charles Pravaz of Lyon also experimented with sub-dermal injections in sheep using a syringe of his own design. Pravaz designed a hypodermic needle measuring 3 cm (1.18 in) long and 5 mm (0.2 in) in diameter; it was made entirely of silver.[13]

Charles Hunter, a London surgeon, is credited with the coining of the term "hypodermic" to describe subcutaneous injection in 1858. The name originates from two Greek words: hypo, "under", and derma, "skin". Furthermore, Hunter is credited with acknowledging the systemic effects of injection after noticing that a patient's pain was alleviated regardless of the injection's proximity to the pained area.[7][8] Hunter and Wood were involved in a lengthy dispute over not only the origin of the modern hypodermic needle, but also because of their disagreement as to the medicine's effect once administered.[14]

Modern improvements

Dr. Francis Rynd (1801–1861) used the first "Hollow Needle" as a hypodermic syringe on Ms. Margaret Cox 6/3/1844 in Ireland. Dr. Wood can be largely credited with the popularization and acceptance of injection as a medical technique, as well as the widespread use and acceptance of the hypodermic needle. The basic technology of the hypodermic needle has stayed largely unchanged since the 19th century, but as the years progressed and medical and chemical knowledge improved, small refinements have been made to increase safety and efficacy, with needles being designed and tailored for very particular uses. Hypodermic needles remain essential to large volume administration or exchange in settings of trauma or dialysis. The trend of needle specification for use began in the 1920s, particularly for the administration of insulin to diabetics.[15]

The onset of World War II spurred the early development of partially disposable syringes for the administration of morphine and penicillin on the battlefield. Development of the fully disposable hypodermic needle was spurred on in the 1950s for several reasons. The Korean War created blood shortages and in response disposable, sterile syringes were developed for collecting blood. The widespread immunization against polio during the period required the development of a fully disposable syringe system.[15]

The 1950s also saw the rise and recognition of cross-contamination from used needles. This led to the development of the first fully disposable plastic syringe by New Zealand pharmacist Colin Murdoch in 1956.[16] This period also marked a shift in interest from needle specifications to general sterility and safety.[15]

The 1980s saw the rise of the HIV epidemic and with it renewed concern over the safety of cross-contamination from used needles. New safety controls were designed on disposable needles to ensure the safety of medical workers in particular. These controls were implemented on the needles themselves, such as retractable needles, but also in the handling of used needles, particularly in the use of hard-surface disposal receptacles found in every medical office today.[15]

By 2008, all-plastic needles were in production and in limited use. One version was made of Vectra (plastic) aromatic liquid crystal polymer tapered from 1.2 mm at the hub to 0.72 mm at the tip (equivalent to 22 gauge metal needle), with an ID/OD ratio of 70%.[17]

Manufacture

Hypodermic needles are normally made from a stainless-steel or Niobium tube[18] through a process known as tube drawing where the tube is drawn through progressively smaller dies to make the needle. The end of the needle is bevelled to create a sharp pointed tip, letting the needle easily penetrate the skin.[19]

A hypodermic needle tip under microscope

Gauge

Six hypodermic needles on Luer connectors. These needles are normally used with other medical devices, such as a syringe; from top to bottom:
  • 26G × 12″ (0.45 × 12 mm) (brown)
  • 25G × 58″ (0.5 × 16 mm) (orange)
  • 22G × 1+14″ (0.7 × 30 mm) (black)
  • 21G × 1+12″ (0.8 × 40 mm) (green)
  • 20G × 1+12″ (0.9 × 40 mm) (yellow)
  • 19G × 1+12″ (1.1 × 40 mm) (cream)
See also Birmingham gauge.

The main system for measuring the diameter of a hypodermic needle is the Birmingham gauge (also known as the Stubs Iron Wire Gauge); the French gauge is used mainly for catheters. Various needle lengths are available for any given gauge. Needles in common medical use range from 7 gauge (the largest) to 33 (the smallest). 21-gauge needles are most commonly used for drawing blood for testing purposes, and 16- or 17-gauge needles are most commonly used for blood donation, as the larger luminal cross-sectional area results in lower fluid shear, reducing harm to red blood cells while also allowing more blood to be collected in a shorter time.[20]

Although reusable needles remain useful for some scientific applications, disposable needles are far more common in medicine. Disposable needles are embedded in a plastic or aluminium hub that attaches to the syringe barrel by means of a press-fit or twist-on fitting. These are sometimes referred to as "Luer Lock" connections, referring to the trademark Luer-Lok. The male and female luer lock and hub—produced by pharmaceutical equipment manufacturers—are two of the most critical parts of disposable hypodermic needles.[21]

Use by non-specialists

Some hypodermic needles used by recreational heroin users

Hypodermic needles are usually used by medical professionals (dentists, phlebotomists, physicians, pharmacists, nurses, paramedics), but they are sometimes used by patients themselves. This is most common with type one diabetics, who may require several insulin injections a day.[22] It also occurs with patients who have asthma or other severe allergies. Such patients may need to take desensitization injections or they may need to carry injectable medicines to use for first aid in case of a severe allergic reaction. In the latter case, such patients often carry a syringe loaded with epinephrine (e.g. EpiPen),[23] diphenhydramine (e.g. Benadryl), or dexamethasone. Rapid injection of one of these drugs may stop a severe allergic reaction.

Multiple sclerosis patients may also treat themselves by injection; several MS therapies, including various interferon preparations, are designed to be self-administered by subcutaneous or intramuscular injection.[24] In some countries, erectile dysfunction patients may be prescribed Alprostadil in injectable form, which is self-injected directly into the base or side of the penis with a very fine hypodermic needle.[citation needed]

Hypodermic needles are also used by untrained users in recreational intravenous drug use (e.g., injecting solutions of heroin and water). Before governments attained current levels of awareness about the spread of disease through shared needles, hypodermic syringes in many countries were available only by prescription. Thus, in order to limit the spread of blood-borne diseases such as hepatitis and HIV through shared injection equipment, many countries have needle exchange programs in most larger cities. In some countries, such programs are wholly or partially subsidized by the government.[citation needed]

Blunt needles, manufactured without a sharp bevel and usually non-sterile, are used industrially for filling small containers or accurately applying small amounts of solvent or glue.

Hypodermic needles are also used for erotic piercing.[25]

Phobia

It is estimated that anywhere from nearly 3.5 to 10% of the world's population may have a phobia of needles (trypanophobia),[26] and it is much more common in children, ages 5–17. Topical anesthetics can be used to desensitize the area where the injection will take place to reduce pain and discomfort.[27] For children various techniques may be effective at reducing distress or pain related to needles.[28] Techniques include: distraction, hypnosis, combined cognitive behavioral therapy, and breathing techniques.[28]

See also

References

  1. ^ "Handling sharps and needles: MedlinePlus Medical Encyclopedia". medlineplus.gov. Retrieved April 4, 2018.
  2. ^ Elsheikh, HA; Ali, BH; Homeida, AM; Lutfi, AA; Hapke, HJ (May–June 1992). "The effects of fascioliasis on the activities of some drug-metabolizing enzymes in desert sheep liver". The British Veterinary Journal. 148 (3): 249–57. doi:10.1016/0007-1935(92)90048-6. PMID 1617399.
  3. ^ Korenman, SG (September 1975). "Estrogen receptor assay in human breast cancer". Journal of the National Cancer Institute. 55 (3): 543–5. doi:10.1093/jnci/55.3.543. PMID 169381.
  4. ^ Scott, Gene E.; Zummo, Natale (January 1, 1988). "Sources of Resistance in Maize to Kernel Infection by Aspergillus flavus in the Field". Crop Science. 28 (3): 504. doi:10.2135/cropsci1988.0011183X002800030016x.
  5. ^ Leuchtmann, Adrian; Clay, Keith (1988). "Experimental Infection of Host Grasses and Sedges with Atkinsonella hypoxylon and Balansia cyperi (Balansiae, Clavicipitaceae)". Mycologia. 80 (3): 291–297. doi:10.2307/3807624. JSTOR 3807624.
  6. ^ a b Norn S, Kruse PR, Kruse E (2006). "On the history of injection". Dan Medicinhist Arbog. 34: 104–1. PMID 17526154.
  7. ^ a b c Kotwal, Atul. "Innovation, diffusion and safety of a medical technology: a review of the literature on injection practice". Social Science & Medicine Volume 60, Issue 5, March 2005, pp. 1133–1147
  8. ^ a b c Ball C (June 2006). "The early development of intravenous apparatus". Anaesthesia and Intensive Care. 34 (Suppl 1): 22–6. doi:10.1177/0310057X0603401S02. PMID 16800224.
  9. ^ Logan Clendening, Source Book of Medical History, p. 419 (1960)
  10. ^ Walter Reginald Bett, The History and Conquest of Common Diseases p. 145 (1954)
  11. ^ "The Irish doctor who invented the syringe". irishtimes.com. Retrieved April 4, 2018.
  12. ^ Kotwal, Atul. "Innovation, diffusion and safety of a medical technology: a review of the literature on injection practices". Social Science & Medicine Volume 60, Issue 5, March 2005, pp. 1133–1147
  13. ^ Syringe, Discoveriesinmedicine.com
  14. ^ Brunton, D. (2000). "A Question of Priority: Alexander Wood, Charles Hunter and the Hypodermic Method". Proceedings of the Royal College of Physicians of Edinburgh. 30 (4): 349–351. doi:10.1177/147827150003000414. S2CID 248921807.
  15. ^ a b c d Beckton Dickinson and Company, "Four Major Phases of Injection Device Development", Syringe and Needle History
  16. ^ "Hypodermic syringe". www.sciencemuseum.org.uk. Archived from the original on July 3, 2012. Retrieved April 4, 2018.
  17. ^ Busillo, Eric (July 9, 2008). Characterization of Plastic Hypodermic Needles (PDF) (Thesis). Georgia Institute of Technology.
  18. ^ How do they get the hole through a hypodermic needle? Archived May 13, 2008, at the Wayback Machine at The Straight Dope.
  19. ^ "How syringe is made - material, production process, manufacture, making, history, used, processing, parts". How Products Are Made. Retrieved January 3, 2018.
  20. ^ Blood Transfusions and Angio Size? Archived 2016-03-03 at the Wayback Machine
  21. ^ "Medical Industry Cycle Times | Davenport Machine". Davenport Machine. Retrieved January 3, 2018.
  22. ^ "Giving an Insulin Injection". Drugs.com. Retrieved August 19, 2010.
  23. ^ "How to Stop Allergic Reactions". EpiPen. Retrieved August 19, 2010.
  24. ^ "Multiple Sclerosis Treatments". mult-sclerosis.org. January 21, 2008. Retrieved January 13, 2013.
  25. ^ Buhrich, Neil (April 1983). "The association of erotic piercing with homosexuality, sadomasochism, bondage, fetishism, and tattoos". Archives of Sexual Behavior. 12 (2): 167–171. doi:10.1007/BF01541560. S2CID 59352980.
  26. ^ "Fear of Needles Phobia – Trypanophobia". www.fearof.net. January 23, 2014. Retrieved January 3, 2018.
  27. ^ "The Needle Phobia Page". Futurescience.com. Retrieved August 19, 2010.
  28. ^ a b Birnie, Kathryn A.; Noel, Melanie; Chambers, Christine T.; Uman, Lindsay S.; Parker, Jennifer A. (October 4, 2018). "Psychological interventions for needle-related procedural pain and distress in children and adolescents". The Cochrane Database of Systematic Reviews. 2020 (10): CD005179. doi:10.1002/14651858.CD005179.pub4. ISSN 1469-493X. PMC 6517234. PMID 30284240.

External links

This page was last edited on 28 March 2024, at 02:51
Basis of this page is in Wikipedia. Text is available under the CC BY-SA 3.0 Unported License. Non-text media are available under their specified licenses. Wikipedia® is a registered trademark of the Wikimedia Foundation, Inc. WIKI 2 is an independent company and has no affiliation with Wikimedia Foundation.