| |
| Names | |
|---|---|
| IUPAC name
(RS)-6-Amino-2-methylheptan-2-ol
| |
| Identifiers | |
3D model (JSmol)
|
|
| ChEBI | |
| ChEMBL | |
| ChemSpider | |
| DrugBank | |
| ECHA InfoCard | 100.006.144 |
| EC Number |
|
| MeSH | Heptaminol |
PubChem CID
|
|
| UNII | |
CompTox Dashboard (EPA)
|
|
| |
| |
| Properties | |
| C8H19NO | |
| Molar mass | 145.246 g·mol−1 |
| Density | 0.895 g/mL |
| Boiling point | 250 °C (482 °F; 523 K) |
| Pharmacology | |
| C01DX08 (WHO) | |
| Oral, intravenous, intramuscular | |
| Pharmacokinetics: | |
| Renal | |
| Hazards | |
| Occupational safety and health (OHS/OSH): | |
Main hazards
|
Corrosive |
| GHS labelling: | |
 
| |
| Danger | |
| H314, H315, H319, H335 | |
| P260, P261, P264, P271, P280, P301+P330+P331, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P310, P312, P321, P332+P313, P337+P313, P362, P363, P403+P233, P405, P501 | |
| Flash point | 105 °C (221 °F; 378 K) |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
| |
Heptaminol is an amino alcohol which is classified as a cardiac stimulant (positive inotropic action). It also increases coronary blood flow along with mild peripheral vasoconstriction. It is sometimes used in the treatment of low blood pressure, particularly orthostatic hypotension as it is a potent positive inotrope (improving cardiac contraction).[medical citation needed]
YouTube Encyclopedic
-
1/5Views:17 65439 1372 12614 75118 128
-
Farmakoloji-Otonom Sinir Sistemi İlaçları 3
-
Imunologia: Aula 13 - Recombinação Somática dos genes dos receptores de antígenos
-
Life science questions and answers for all competitive exams||Part-5
-
Reet 2020/teaching methos model paper/teaching method level 1/teaching method level 2/reet exam 2020
-
Pharma Tube - 28 - CVS - 5 - Hypotension and Antihypotensive Drugs [HD]
Transcription
Use in doping
Heptaminol is classified by the World Anti-Doping Agency as a doping substance.[1] In 2008, the cyclist Dmitriy Fofonov tested positive for heptaminol at the Tour de France.[2] In June 2010, the swimmer Frédérick Bousquet tested positive.[3] In 2013, the cyclist Sylvain Georges tested positive at the Giro d'Italia.[4] In 2014, baseball player Joel Piniero tested positive[5] as well as St. Louis Cardinals minor league baseball player Yeison Medina.[6]
On March 22, 2019, Cycling South Africa reported that Ricardo Broxham has been sanctioned for an anti-doping rule violation of Articles 2.1 and 2.2 of the UCI Anti-Doping Rules after an in-competition test conducted on 18 August 2018 confirmed the presence of Heptaminol in his sample.
The UCI Anti-Doping Tribunal has imposed a period of ineligibility of 12 months for the violation, applicable as of 22 September 2018 up to and including 22 September 2019 and a disqualification of all results from the 2018 UCI Junior Track Cycling World Championships.[7]
See also
References
- ^ "Prohibited in Competition". WADA.
- ^ "Tour rider Fofonov tests positive". BBC. 2008-07-28. Retrieved 2008-07-28.
- ^ "France swimmer Bousquet suspended in doping scandal". France24. 2010-10-24. Retrieved 2010-10-23.
- ^ "French rider Sylvain Georges tests positive at Giro". ESPN. 2013-05-16. Retrieved 2013-05-16.
- ^ "Joel Pineiro suspended 50 games". ESPN. 2014-06-30. Retrieved 2014-06-30.
- ^ "Yeison Medina suspended 50 games". ESPN. 2014-09-16. Retrieved 2014-09-16.
- ^ "Anti-Doping Rule Violation – In-competition test". Cycling South Africa. Retrieved 2019-03-24.
This page was last edited on 28 November 2021, at 20:43