| Clinical data | |
|---|---|
| Trade names | Omegaven |
| Other names | Fish oil triglycerides |
| AHFS/Drugs.com | Professional Drug Facts |
| License data | |
| Pregnancy category |
|
| Dependence liability | Intravenous |
| Drug class | Intravenous nutritional products |
| ATC code |
|
| Legal status | |
| Legal status | |
Fish oil, sold under the brand name Omegaven, is a fatty acid emulsion.[2] It is used for total parenteral nutrition (feeding directly into a venous catheter), e.g. in short bowel syndrome.[2] It is rich in omega-3 fatty acids.[2]
Fish oil triglycerides was approved for use in the United States in July 2018,[3] and is available to people on the US market by prescription effective November 2018.[4]
In 2021, it was the 283rd most commonly prescribed medication in the United States, with more than 700,000 prescriptions.[5][6]
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Transcription
Research
It has gained popularity in children in preference to the more commonly used intralipid after case reports that it reduced the risk of liver damage.[7]
A 2007, study indicated that the use of Omegaven may be an appropriate intervention strategy for newborns with a very low birth weight, gastroschisis, and intestinal atresia.[8]
A clinical trial exploring the use of fish oil as an adjunct to parenteral nutrition in surgical intensive care units at National Taiwan University Hospital completed in March 2007.[9]
Although the use of fish oil triglycerides in children in the United States is experimental, the use of it in adults in Europe is less controversial.[10] In European studies, fish oil triglycerides have been associated with a reduction in psoriasis, when contrasted to administration of omega-6 fatty acid Lipoven.[11] Fish oil triglycerides have also been associated with reduced mortality and antibiotic use during hospital stays.[12]
References
- ^ "Fat emulsion Use During Pregnancy". Drugs.com. 4 May 2020. Retrieved 12 May 2020.
- ^ a b c d "Omegaven- fish oil injection, emulsion". DailyMed. 6 August 2018. Retrieved 13 May 2020.
- ^ "Drug Approval Package: Omegaven (fish oil triglycerides)". U.S. Food and Drug Administration (FDA). 24 August 2018. Retrieved 12 May 2020.
- ^ Research, Center for Drug Evaluation and. "Investigational New Drug (IND) Application - How to request Omegaven for Expanded Access Use". www.fda.gov. Retrieved 15 February 2019.
- ^ "The Top 300 of 2021". ClinCalc. Archived from the original on 15 January 2024. Retrieved 14 January 2024.
- ^ "Fish Oil - Drug Usage Statistics". ClinCalc. Retrieved 14 January 2024.
- ^ Gura KM, Duggan CP, Collier SB, et al. (2006). "Reversal of parenteral nutrition-associated liver disease in two infants with short bowel syndrome using parenteral fish oil: implications for future management". Pediatrics. 118 (1): e197–201. doi:10.1542/peds.2005-2662. PMID 16818533. S2CID 46567040.
- ^ Christensen RD, Henry E, Wiedmeier SE, Burnett J, Lambert DK (2007). "Identifying patients, on the first day of life, at high-risk of developing parenteral nutrition-associated liver disease". Journal of Perinatology. 27 (5): 284–90. doi:10.1038/sj.jp.7211686. PMID 17344923. S2CID 12613845.
- ^ Clinical trial number NCT00172198 for "Omegaven (w-3 Fish Oil) Supplemented Parenteral Nutrition in Subjects of SICU." at ClinicalTrials.gov
- ^ A Doctor's Push For Drug Pits Him Against Its Maker at The Wall Street Journal
- ^ Mayser P, Grimm H, Grimminger F (2002). "n-3 fatty acids in psoriasis". Br. J. Nutr. 87. Suppl 1: S77–82. doi:10.1079/bjn2001459. PMID 11895157.
- ^ Heller AR, Rössler S, Litz RJ, et al. (2006). "Omega-3 fatty acids improve the diagnosis-related clinical outcome". Crit. Care Med. 34 (4): 972–9. doi:10.1097/01.CCM.0000206309.83570.45. PMID 16484909. S2CID 32537029.
External links
- Cooke, Robert (3 July 2006). "How fish oil may have saved babies' lives". The Boston Globe. Retrieved 22 August 2007.
- "The Right Kind of Oil" Archived 27 September 2007 at the Wayback Machine at Children's Hospital Boston
- Team on a Mission at Toronto Star
- Old Fashioned Lifeline Boston Globe 1/9/2009
- rockcenter.nbcnews.com: drug treatment omegaven that could save infants lives not yet approved by fda
This page was last edited on 9 February 2024, at 23:08