![James Holland, a renowned cancer expert who was a major figure in the development of cancer chemotherapy, died on March 22, 2018, at the age of 92. Dr. Holland was among the first group of research physicians recruited to the NIH Clinical Center, serving as a senior surgeon at the National Cancer Institute from 1953 to 1954. In that short year at the NIH, he initiated a clinical trial to compare continuous or intermittent treatment with two chemotherapy agents for acute leukemia in children: methotrexate and 6-mercaptopurine. Photo courtesy: National Library of Medicine: <a href="http://resource.nlm.nih.gov/101441421" rel="nofollow">resource.nlm.nih.gov/101441421</a> : Image ID: B09668](http://upload.wikimedia.org/wikipedia/commons/thumb/7/72/James_F._Holland%2C_1925-2018_%2840326125914%29.jpg/479px-James_F._Holland%2C_1925-2018_%2840326125914%29.jpg)
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