To install click the Add extension button. That's it.

The source code for the WIKI 2 extension is being checked by specialists of the Mozilla Foundation, Google, and Apple. You could also do it yourself at any point in time.

Kelly Slayton
Congratulations on this excellent venture… what a great idea!
Alexander Grigorievskiy
I use WIKI 2 every day and almost forgot how the original Wikipedia looks like.
What we do. Every page goes through several hundred of perfecting techniques; in live mode. Quite the same Wikipedia. Just better.

From Wikipedia, the free encyclopedia

Feodor Felix Konrad Lynen
Feodor Lynen with pipette.jpg
Born6 April 1911
Died6 August 1979(1979-08-06) (aged 68)
AwardsNobel Prize in Physiology or Medicine (1964)
Fellow of the Royal Society[1]

Feodor Felix Konrad Lynen ForMemRS[1] (6 April 1911 – 6 August 1979) was a German biochemist. In 1964 he won the Nobel Prize in Physiology or Medicine together with Konrad Bloch for their discoveries concerning the mechanism and regulation of cholesterol and fatty acid metabolism while he was director of the Max-Planck Institute for Cellular Chemistry in Munich.


Feodor Lynen was born in Munich on 6 April 1911. He started his studies at the chemistry department of Munich University in 1930 and graduated in March 1937 under Heinrich Wieland with the work: "On the Toxic Substances in Amanita". Lynen remained in Germany throughout World War II. In 1942 he became a chemistry lecturer at the Munich University. In 1947 he became an assistant professor and in 1953 a professor of biochemistry. From 1954 onwards he was director of the Max-Planck Institute for Cellular Chemistry in Munich, a position which was created for him at the instigation of two senior scientists, Otto Warburg and Otto Hahn. In 1972, that institute was merged into the newly founded Max-Planck Institute of Biochemistry in 1972. Also in 1972, Lynen was named President of the Gesellschaft Deutscher Chemiker (GDCh).[2]

In 1964 he won the Nobel Prize in Physiology or Medicine together with Konrad Bloch for their discoveries concerning the mechanism and regulation of cholesterol and fatty acid metabolism. These discoveries took many years to work out.[3][4][5][6] The Nobel Committee felt that this was important because understanding the metabolism of sterols and fatty acids could reveal how cholesterol affects heart disease and stroke.[7] His Nobel Lecture on 11 December 1964 was 'The pathway from "activated acetic acid" to the terpenes and fatty acids'.[8]

Working mostly separately, Lynen and Bloch both discovered the steps that created squalene and turned the squalene into cholesterol. Initially, Lynen found that acetate activated by Coenzyme A was needed to start the process. He discovered the chemical structure of acetyl-coenzyme A, which was needed for a detailed understanding of the biochemical pathways.[7] He also learned that biotin, or Vitamin B7, was needed for in the process.[8]

Lynen with family in Stockholm in 1964
Lynen with family in Stockholm in 1964

On 14 May 1937, Lynen married Eva Wieland (1915–2002), daughter of his academic teacher. They had five children between 1938 and 1946.[2] Feodor Lynen died in Munich, Germany, on 6 August 1979, six weeks after an operation for aneurism.[7]


The Alexander von Humboldt Foundation has a fellowship named in his honor.

Honours and awards


  1. ^ a b Krebs, H.; Decker, K. (1982). "Feodor Lynen. 6 April 1911-6 August 1979". Biographical Memoirs of Fellows of the Royal Society. 28: 261–317. doi:10.1098/rsbm.1982.0012. JSTOR 769901.
  2. ^ a b "Feodor Lynen — Biographical". Nobel Media AB. Retrieved 13 November 2013.
  3. ^ Bucher NL, Overath P, Lynen F (June 1960). "beta-Hydroxy-beta-methyl-glutaryl coenzyme A reductase, cleavage and condensing enzymes in relation to cholesterol formation in rat liver". Biochimica et Biophysica Acta. 40: 491–501. doi:10.1016/0006-3002(60)91390-1. PMID 13805544.
  4. ^ Lynen F (July 1966). "The biochemical basis of the biosynthesis of cholesterol and fatty acids". Wiener Klinische Wochenschrift (in German). 78 (27): 489–97. PMID 4296920.
  5. ^ Back P, Hamprecht B, Lynen F (August 1969). "Regulation of cholesterol biosynthesis in rat liver: diurnal changes of activity and influence of bile acids". Archives of Biochemistry and Biophysics. 133 (1): 11–21. doi:10.1016/0003-9861(69)90482-2. PMID 5810824.
  6. ^ Hamprecht B, Nüssler C, Waltinger G, Lynen F (January 1971). "Influence of bile acids on the activity of rat liver 3-hydroxy-3-methylglutaryl coenzyme A reductase. 1. Effect of bile acids in vitro and in vivo". European Journal of Biochemistry. 18 (1): 10–4. doi:10.1111/j.1432-1033.1971.tb01207.x. PMID 5547468.
  7. ^ a b c "Feodor Lynen Biography (1911–1979)". Internet FAQ Archives. Retrieved 13 November 2013.
  8. ^ a b Lynen, Fyodor (11 December 1964). "The pathway from 'activated acetic acid' to the terpenes and fatty acids". Nobel Media AB.
  9. ^ "Otto-Warburg-Medal". GBM. Archived from the original on 4 November 2016. Retrieved 12 January 2014.

External links

This page was last edited on 8 January 2021, at 03:31
Basis of this page is in Wikipedia. Text is available under the CC BY-SA 3.0 Unported License. Non-text media are available under their specified licenses. Wikipedia® is a registered trademark of the Wikimedia Foundation, Inc. WIKI 2 is an independent company and has no affiliation with Wikimedia Foundation.