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Diflorasone diacetate

From Wikipedia, the free encyclopedia

Diflorasone diacetate
Clinical data
Trade namesPsorcon
AHFS/Drugs.comMonograph
MedlinePlusa602019
License data
Routes of
administration		Topical
ATC code
Legal status
Legal status
Identifiers
  • [17-(2-Acetyloxyacetyl)- 6,9-difluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16- octahydrocyclopenta[a]phenanthren-17-yl] acetate
CAS Number
PubChem CID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.046.872 Edit this at Wikidata
Chemical and physical data
FormulaC26H32F2O7
Molar mass494.532 g·mol−1
  • InChI=1S/C26H32F2O7/c1-13-8-17-18-10-20(27)19-9-16(31)6-7-23(19,4)25(18,28)21(32)11-24(17,5)26(13,35-15(3)30)22(33)12-34-14(2)29/h6-7,9,13,17-18,20-21,32H,8,10-12H2,1-5H3/t13-,17-,18-,20-,21-,23-,24-,25-,26-/m0/s1 checkY
  • Key:BOBLHFUVNSFZPJ-JOYXJVLSSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Diflorasone diacetate is a topical steroid that comes in the form of a cream. It is manufactured by E. Fougera & Co. and is used as an anti-inflammatory and anti-itching agent, like other topical corticosteroids. It is prescribed for psoriasis[1] and atopic dermatitis, among other conditions. With respect to potency, it is regarded as a Class I corticosteroid [of classes I – VII] in the United States.[2]

No long-term animal studies have been done to determine whether diflorasone diacetate could have carcinogenic properties.[citation needed]

Little data is available regarding whether diflorasone diacetate would be present in great enough quantities to cause harm to an infant.[3]

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Transcription

References

  1. ^ Shupack JL, Jondreau L, Kenny C, Stiller MJ (1993). "Diflorasone diacetate ointment 0.05% versus betamethasone dipropionate ointment 0.05% in moderate-severe plaque-type psoriasis". Dermatology. 186 (2): 129–32. doi:10.1159/000247323. PMID 8428041.
  2. ^ "Topical Steroids Potency Chart". psoriasis.org.
  3. ^ "Diflorasone topical". Drugs.com.

External links


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This page was last edited on 29 June 2022, at 18:51
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