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Cyanopindolol

From Wikipedia, the free encyclopedia

Cyanopindolol
Skeletal formula of cyanopindolol
Space-filling model of the cyanopindolol molecule
Clinical data
ATC code
  • none
Identifiers
  • (RS)-4-[3-(tert-Butylamino)-2-hydroxypropoxy]-1H-indole-2-carbonitrile
CAS Number
PubChem CID
IUPHAR/BPS
ChemSpider
UNII
ChEMBL
PDB ligand
Chemical and physical data
FormulaC16H21N3O2
Molar mass287.363 g·mol−1
3D model (JSmol)
ChiralityRacemic mixture
  • N#CC1=CC2=C(OCC(CNC(C)(C)C)O)C=CC=C2N1
  • InChI=1S/C16H21N3O2/c1-16(2,3)18-9-12(20)10-21-15-6-4-5-14-13(15)7-11(8-17)19-14/h4-7,12,18-20H,9-10H2,1-3H3 ☒N
  • Key:QXIUMMLTJVHILT-UHFFFAOYSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

Cyanopindolol is a drug related to pindolol which acts as both a β1 adrenoceptor antagonist and a 5-HT1A receptor antagonist. Its radiolabelled derivative iodocyanopindolol has been widely used in mapping the distribution of beta adrenoreceptors in the body.[1]

References

  1. ^ Hoyer D, Engel G (1983). "Binding of 125I-cyanopindolol to beta-1-adrenoceptors in a high and low affinity state". Journal of Receptor Research. 3 (1–2): 45–59. doi:10.3109/10799898309041922. PMID 6304308.
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This page was last edited on 18 July 2023, at 09:10
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