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Cicloprolol

From Wikipedia, the free encyclopedia

Cicloprolol
Names
IUPAC name
1-[4-[2-(Cyclopropylmethoxy)ethoxy]phenoxy]-3-(propan-2-ylamino)propan-2-ol
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
KEGG
UNII
  • InChI=1S/C18H29NO4/c1-14(2)19-11-16(20)13-23-18-7-5-17(6-8-18)22-10-9-21-12-15-3-4-15/h5-8,14-16,19-20H,3-4,9-13H2,1-2H3
    Key: JNDJPKHYZWRRIS-UHFFFAOYSA-N
  • CC(C)NCC(COC1=CC=C(C=C1)OCCOCC2CC2)O
Properties
C18H29NO4
Molar mass 323.433 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Cicloprolol is a beta-adrenoceptor antagonist.[1]

Synthesis

Cicloprolol synthesis:[2][3]

See also

References

  1. ^ Cocco, G; Alfiero, R; Pouleur, H (1992). "An evaluation of the safety of the beta-modulator cicloprolol in chronic heart failure". Clinical Cardiology. 15 (1): 38–42. doi:10.1002/clc.4960150109. PMID 1347258.
  2. ^ DE 2649605, Manoury, Philippe Michel Jacques; Cavero, Icilio Angelo Girolamo & Majer, Henry et al., "Phenoläther, Verfahren zu ihrer Herstellung und sie enthaltende Arzneimttel [Phenol ethers, processes for their preparation and medicinal products containing them]", published 1977-05-18, assigned to Synthelabo S.A. 
  3. ^ P. M. J. Manouri, I. A. G. Carero, H. Majer, and P. R. L. Giudicelli, (1977) Chem. Abstr., 87:134,543j (1977). eidem U.S. Patent 4,311,708


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This page was last edited on 16 February 2022, at 17:41
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