Carbon-monoxide dehydrogenase (ferredoxin)

In enzymology, a carbon-monoxide dehydrogenase (ferredoxin) (EC 1.2.7.4) is an enzyme that catalyzes the chemical reaction

CO + H₂O + oxidized ferredoxin ${\displaystyle \rightleftharpoons }$ CO₂ + reduced ferredoxin

The three substrates of this enzyme are CO, H₂O, and oxidized ferredoxin, whereas its two products are CO₂ and reduced ferredoxin.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with an iron-sulfur protein as acceptor. The systematic name of this enzyme class is carbon-monoxide,water:ferredoxin oxidoreductase.

References

• Meyer O, Schlegel HG (1980). "Carbon monoxide:methylene blue oxidoreductase from Pseudomonas carboxydovorans". Journal of Bacteriology. 141 (1): 74–80. doi:10.1128/jb.141.1.74-80.1980. PMC 293533. PMID 7354006.
• Ragsdale SW, Clark JE, Ljungdahl LG, Lundie LL, Drake HL (1983). "Properties of purified carbon monoxide dehydrogenase from Clostridium thermoaceticum, a nickel, iron-sulfur protein". Journal of Biological Chemistry. 258 (4): 2364–9. doi:10.1016/S0021-9258(18)32932-6. PMID 6687389.
• Doukov TI, Iverson TM, Seravalli J, Ragsdale SW, Drennan CL (2002). "A Ni-Fe-Cu center in a bifunctional carbon monoxide dehydrogenase/acetyl-CoA synthase". Science. 298 (5593): 567–72. Bibcode:2002Sci...298..567D. doi:10.1126/science.1075843. PMID 12386327.

This page was last edited on 8 April 2024, at 07:48