CTTNBP2NL

CTTNBP2NL

Identifiers

CTTNBP2NL, CTTNBP2 N-terminal like

External IDs

OMIM: 615100 MGI: 1933137 HomoloGene: 36371 GeneCards: CTTNBP2NL

Gene location (Human)

Chr.	Chromosome 1 (human)^[1]

Band	1p13.2	Start	112,396,214 bp^[1]
Band	1p13.2	End	112,463,456 bp^[1]

Gene location (Mouse)

Chr.	Chromosome 3 (mouse)^[2]

Band	3\|3 F2.2	Start	104,909,231 bp^[2]
Band	3\|3 F2.2	End	104,960,462 bp^[2]

RNA expression pattern

Bgee

Human

Mouse (ortholog)

Top expressed in

secondary oocyte

amniotic fluid

pancreatic epithelial cell

sural nerve

gums

visceral pleura

endothelial cell

human penis

oral cavity

vulva

Top expressed in

trigeminal ganglion

sciatic nerve

secondary oocyte

left lung lobe

primitive streak

fossa

right lung lobe

substantia nigra

carotid body

sexually immature organism

More reference expression data

BioGPS

n/a

Gene ontology
Molecular function	protein phosphatase 2A binding protein binding
Cellular component	cytoplasm actin cytoskeleton cytoskeleton
Biological process	protein dephosphorylation negative regulation of transporter activity negative regulation of transmembrane transport
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse

Entrez


55917


80281

Ensembl


ENSG00000143079


ENSMUSG00000062127

UniProt


Q9P2B4


Q99LJ0

RefSeq (mRNA)


NM_018704


NM_001163332 NM_001163333 NM_030249

RefSeq (protein)


NP_061174


NP_001156804 NP_001156805 NP_084525

Location (UCSC)

Chr 1: 112.4 – 112.46 Mb

Chr 3: 104.91 – 104.96 Mb

PubMed search

^[3]

^[4]

Wikidata

View/Edit Human

View/Edit Mouse

CTTNBP2 N-terminal-like protein is a protein that in humans is encoded by the CTTNBP2NL gene.^[5]^[6] It is a substrate for phosphorylation.^[7]

Interactions

CTTNBP2NL has been shown to interact with:

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000143079 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000062127 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Nagase T, Kikuno R, Ishikawa KI, Hirosawa M, Ohara O (Feb 2000). "Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro". DNA Research. 7 (1): 65–73. doi:10.1093/dnares/7.1.65. PMID 10718198.
^ "Entrez Gene: CTTNBP2NL CTTNBP2 N-terminal like".
^ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ ^j Goudreault M, D'Ambrosio LM, Kean MJ, Mullin MJ, Larsen BG, Sanchez A, Chaudhry S, Chen GI, Sicheri F, Nesvizhskii AI, Aebersold R, Raught B, Gingras AC (Jan 2009). "A PP2A phosphatase high density interaction network identifies a novel striatin-interacting phosphatase and kinase complex linked to the cerebral cavernous malformation 3 (CCM3) protein". Molecular & Cellular Proteomics. 8 (1): 157–71. doi:10.1074/mcp.M800266-MCP200. PMC 2621004. PMID 18782753.

External links

Human CTTNBP2NL genome location and CTTNBP2NL gene details page in the UCSC Genome Browser.

Hartley JL, Temple GF, Brasch MA (Nov 2000). "DNA cloning using in vitro site-specific recombination". Genome Research. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
Simpson JC, Wellenreuther R, Poustka A, Pepperkok R, Wiemann S (Sep 2000). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Reports. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
Beausoleil SA, Jedrychowski M, Schwartz D, Elias JE, Villén J, Li J, Cohn MA, Cantley LC, Gygi SP (Aug 2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proceedings of the National Academy of Sciences of the United States of America. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
Ballif BA, Villén J, Beausoleil SA, Schwartz D, Gygi SP (Nov 2004). "Phosphoproteomic analysis of the developing mouse brain". Molecular & Cellular Proteomics. 3 (11): 1093–101. doi:10.1074/mcp.M400085-MCP200. PMID 15345747.
Wiemann S, Arlt D, Huber W, Wellenreuther R, Schleeger S, Mehrle A, Bechtel S, Sauermann M, Korf U, Pepperkok R, Sültmann H, Poustka A (Oct 2004). "From ORFeome to biology: a functional genomics pipeline". Genome Research. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
Mehrle A, Rosenfelder H, Schupp I, del Val C, Arlt D, Hahne F, Bechtel S, Simpson J, Hofmann O, Hide W, Glatting KH, Huber W, Pepperkok R, Poustka A, Wiemann S (Jan 2006). "The LIFEdb database in 2006". Nucleic Acids Research. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
Beausoleil SA, Villén J, Gerber SA, Rush J, Gygi SP (Oct 2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nature Biotechnology. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243. S2CID 14294292.

This article on a gene on human chromosome 1 is a stub. You can help Wikipedia by expanding it.

This page was last edited on 3 January 2024, at 06:48

From Wikipedia, the free encyclopedia

Interactions

References

External links

Further reading