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Recent Advances in Hepatology Programme | Clinics in Hepato-Biliary Diseases 2020 | SGRH
Module XIV-B Preview: Comprehensive Weight Loss for the Integrative Physician
ალექსი ამნიაშვილი - Back End-ის საბაზისო კურსი (I ლექცია)
Transcription
Function
This gene encodes the alpha chain of type XVI collagen, a member of the FACIT collagen family (fibril-associated collagens with interrupted helices). Members of this collagen family are found in association with fibril-forming collagens such as type I and II, and serve to maintain the integrity of the extracellular matrix. High levels of type XVI collagen have been found in fibroblasts and keratinocytes, and in smooth muscle and amnion.[6]
Yamaguchi N, Kimura S, McBride OW, Hori H, Yamada Y, Kanamori T, Yamakoshi H, Nagai Y (1993). "Molecular cloning and partial characterization of a novel collagen chain, alpha 1(XVI), consisting of repetitive collagenous domains and cysteine-containing non-collagenous segments". J. Biochem. 112 (6): 856–63. doi:10.1093/oxfordjournals.jbchem.a123989. PMID1284248.
Ratzinger S, Grässel S, Dowejko A, Reichert TE, Bauer RJ (2011). "Induction of type XVI collagen expression facilitates proliferation of oral cancer cells". Matrix Biology. 30 (2): 118–25. doi:10.1016/j.matbio.2011.01.001. PMID21251976.
Tillet E, Mann K, Nischt R, Pan TC, Chu ML, Timpl R (1995). "Recombinant analysis of human alpha 1 (XVI) collagen. Evidence for processing of the N-terminal globular domain". Eur. J. Biochem. 228 (1): 160–8. doi:10.1111/j.1432-1033.1995.tb20245.x. PMID7882999.
Ratzinger S, Grässel S, Dowejko A, Reichert TE, Bauer RJ (March 2011). "Induction of type XVI collagen expression facilitates proliferation of oral cancer cells". Matrix Biology. 30 (2): 118–25. doi:10.1016/j.matbio.2011.01.001. PMID21251976.
Kassner A, Hansen U, Miosge N, Reinhardt DP, Aigner T, Bruckner-Tuderman L, Bruckner P, Grässel S (2004). "Discrete integration of collagen XVI into tissue-specific collagen fibrils or beaded microfibrils". Matrix Biol. 22 (2): 131–43. doi:10.1016/S0945-053X(03)00008-8. PMID12782140.
Kassner A, Tiedemann K, Notbohm H, Ludwig T, Mörgelin M, Reinhardt DP, Chu ML, Bruckner P, Grässel S (2004). "Molecular structure and interaction of recombinant human type XVI collagen". J. Mol. Biol. 339 (4): 835–53. doi:10.1016/j.jmb.2004.03.042. PMID15165854.
This page was last edited on 21 November 2023, at 21:12