CAP2

CAP2
Identifiers
Aliases	CAP2, CAP, adenylate cyclase-associated protein, 2 (yeast), cyclase associated actin cytoskeleton regulatory protein 2
External IDs	OMIM: 618385 MGI: 1914502 HomoloGene: 101397 GeneCards: CAP2
Gene location (Human) Chr. Chromosome 6 (human)[1] Band 6p22.3 Start 17,393,595 bp[1] End 17,557,780 bp[1]
Gene location (Mouse) Chr. Chromosome 13 (mouse)[2] Band 13|13 A5 Start 46,655,324 bp[2] End 46,803,757 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in Brodmann area 23 vastus lateralis muscle endothelial cell deltoid muscle gastrocnemius muscle frontal pole tibialis anterior muscle triceps brachii muscle middle temporal gyrus Brodmann area 10 Top expressed in triceps brachii muscle vastus lateralis muscle temporal muscle olfactory tubercle primary motor cortex dentate gyrus Region I of hippocampus proper gastrocnemius muscle superior frontal gyrus cingulate gyrus More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding actin binding adenylate cyclase binding identical protein binding Cellular component plasma membrane membrane cortical actin cytoskeleton postsynaptic density Biological process establishment or maintenance of cell polarity cytoskeleton organization signal transduction activation of adenylate cyclase activity actin polymerization or depolymerization cell morphogenesis regulation of adenylate cyclase activity Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 10486 67252 Ensembl ENSG00000112186 ENSMUSG00000021373 UniProt P40123 Q9CYT6 RefSeq (mRNA) NM_006366 NM_001363533 NM_001363534 NM_026056 RefSeq (protein) NP_006357 NP_001350462 NP_001350463 NP_080332 Location (UCSC) Chr 6: 17.39 – 17.56 Mb Chr 13: 46.66 – 46.8 Mb PubMed search [3] [4]
Wikidata
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Adenylyl cyclase-associated protein 2 is an enzyme that in humans is encoded by the CAP2 gene.^[5][6][7]

Function

This gene was identified by its similarity to the gene for human adenylyl cyclase-associated protein. The function of the protein encoded by this gene is unknown. However, the protein appears to be able to interact with adenylyl cyclase-associated protein and actin.^[7]

Interactions

CAP2 has been shown to interact with CAP1.^[6]

References

External links

• Human CAP2 genome location and CAP2 gene details page in the UCSC Genome Browser.

Further reading

This article on a gene on human chromosome 6 is a stub. You can help Wikipedia by expanding it.

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This page was last edited on 16 January 2024, at 13:14