To install click the Add extension button. That's it.

The source code for the WIKI 2 extension is being checked by specialists of the Mozilla Foundation, Google, and Apple. You could also do it yourself at any point in time.

How to transfigure the Wikipedia

Would you like Wikipedia to always look as professional and up-to-date? We have created a browser extension. It will enhance any encyclopedic page you visit with the magic of the WIKI 2 technology.

Try it — you can delete it anytime.

Install in 5 seconds
4,5
Kelly Slayton
Congratulations on this excellent venture… what a great idea!
Alexander Grigorievskiy
I use WIKI 2 every day and almost forgot how the original Wikipedia looks like.
Live Statistics
English Articles
Improved in 24 Hours
Added in 24 Hours
What we do. Every page goes through several hundred of perfecting techniques; in live mode. Quite the same Wikipedia. Just better.
Great Wikipedia has got greater.
.
Leo
Newton
Brights
Milds

Befuraline

From Wikipedia, the free encyclopedia

Befuraline
Clinical data
ATC code
  • none
Identifiers
  • 1-benzofuran-2-yl(4-benzylpiperazin-1-yl)methanone
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC20H20N2O2
Molar mass320.392 g·mol−1
3D model (JSmol)
  • O=C(N1CCN(CC1)CC2=CC=CC=C2)C3=CC4=C(C=CC=C4)O3
  • InChI=1S/C20H20N2O2/c23-20(19-14-17-8-4-5-9-18(17)24-19)22-12-10-21(11-13-22)15-16-6-2-1-3-7-16/h1-9,14H,10-13,15H2 checkY
  • Key:SRIJFPBZWUFLFD-UHFFFAOYSA-N checkY
  (verify)

Befuraline (DIV-154) is a psychoactive drug and member of the piperazine chemical class which was developed in Germany in the 1970s.[1] Befuraline has stimulant and antidepressant effects and has seen some use in Germany and France, although it has never become widely used.[2] Befuraline's active metabolite benzylpiperazine is likely to contribute to its effects.

YouTube Encyclopedic

  • 1/4
    Views:
    28 344
    113 201
    53 287
    17 806
  • Tranquilizers: "The Relaxed Wife" 1957 Roerig-Pfizer Atarax ( Hydroxyzine )
  • The Health Benefits of a Vitamin B Complex (Comprehensive Review)
  • Syrup Manufacturing Process
  • Multivitamins Plus Iron - Daily Vitamins A B1 B2 Review

Transcription

Synthesis

Synthesis:[1] Patent:[3]

A one-step coupling between coumarilic acid (benzofuran-2-carboxylic acid) [496-41-3] (1) and benzylpiperazine (BzP) (2) gives an amide, and hence Befuraline (3).

See also

References

  1. ^ a b Boksay IJ, Popendiker K, Weber RO, Söder A (1979). "Synthesis and pharmacological activity of befuraline (N-benzo[b]furan-2-ylcarbonyl-N'-benzylpiperazine), a new antidepressant compound". Arzneimittel-Forschung. 29 (2): 193–204. PMID 582130.
  2. ^ Gastpar M, Gastpar G, Gilsdorf U (November 1985). "Befuraline, its safety and efficacy in depressed inpatients". Pharmacopsychiatry. 18 (6): 351–5. doi:10.1055/s-2007-1017396. PMID 4089015. S2CID 9322026.
  3. ^ DE2157424 idem Rolf-Ortwin Weber, Alfons Soder, Istvan Boksay, U.S. Patent 4,374,990 (1980 to Hoechst Aktiengesellschaft).


Stub icon

This psychoactive drug-related article is a stub. You can help Wikipedia by expanding it.

This page was last edited on 11 January 2024, at 09:57
Basis of this page is in Wikipedia. Text is available under the CC BY-SA 3.0 Unported License. Non-text media are available under their specified licenses. Wikipedia® is a registered trademark of the Wikimedia Foundation, Inc. WIKI 2 is an independent company and has no affiliation with Wikimedia Foundation.
Contact WIKI 2
Introduction
Terms of Service
Privacy Policy