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Aranidipine

From Wikipedia, the free encyclopedia

Aranidipine
Skeletal formula of aranidipine
Ball-and-stick model of the aranidipine molecule
Clinical data
AHFS/Drugs.comInternational Drug Names
Routes of
administration		Oral
ATC code
  • none
Legal status
Legal status
  • In general: ℞ (Prescription only)
Identifiers
  • O5-methyl O3-(2-oxopropyl)
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC19H20N2O7
Molar mass388.376 g·mol−1
3D model (JSmol)
  • CC1=C(C(C(=C(N1)C)C(=O)OCC(=O)C)C2=CC=CC=C2[N+](=O)[O-])C(=O)OC
  • InChI=1S/C19H20N2O7/c1-10(22)9-28-19(24)16-12(3)20-11(2)15(18(23)27-4)17(16)13-7-5-6-8-14(13)21(25)26/h5-8,17,20H,9H2,1-4H3 checkY
  • Key:NCUCGYYHUFIYNU-UHFFFAOYSA-N checkY
  (verify)

Aranidipine (INN, trade name Sapresta) is a calcium channel blocker. It is a dihydropyridine derivative with two active metabolites (M-1α and M-1β). It was developed by Maruko Seiyaku and has the formula methyl 2-oxopropyl 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylate. Its main use is as a hypotensive, reducing blood pressure.[1][2]

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Transcription

References

  1. ^ "Aranidipine". PubMed. Retrieved 23 December 2018.
  2. ^ Gelatsis P (1997). "To Market, to Market – 1996". In Bristol JA, Robertson DW, Doherty AM, Hagmann WK, Plattner JJ, Wong WW, Trainor GL (eds.). Annual Reports in Medicinal Chemistry. San Diego: Academic Press. p. 306. ISBN 978-0-08-058376-1.
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This page was last edited on 7 January 2024, at 22:21
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