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Annonamine

From Wikipedia, the free encyclopedia

Annonamine
Names
Preferred IUPAC name
(6aR)-2-Hydroxy-1-methoxy-6,6-dimethyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-6-ium
Identifiers
3D model (JSmol)
ChemSpider
UNII
  • InChI=1S/C19H21NO2/c1-20(2)9-8-13-11-16(21)19(22-3)18-14-7-5-4-6-12(14)10-15(20)17(13)18/h4-7,11,15H,8-10H2,1-3H3/p+1/t15-/m1/s1
    Key: WWSQXPANNACSIL-OAHLLOKOSA-O
  • InChI=1S/C19H21NO2/c1-20(2)9-8-13-11-16(21)19(22-3)18-14-7-5-4-6-12(14)10-15(20)17(13)18/h4-7,11,15H,8-10H2,1-3H3/p+1/t15-/m1/s1
    Key: WWSQXPANNACSIL-XRLFSOBABS
  • C[N+]1(C)CCC2=CC(O)=C(OC)C3=C2[C@H]1CC4=C3C=CC=C4
Properties
C19H22NO2
Molar mass 296.390 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Annonamine is a benzylisoquinoline alkaloid isolated from Annona muricata[1] (commonly known as soursop, graviola, guanabana, paw-paw and sirsak), a plant commonly used in folk medicine by indigenous communities in Africa and South America.[2] Structurally, it contains an aporphine core featuring a quaternary ammonium group.

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Transcription

See also

References

  1. ^ Matsushige, A; Kotake, Y; Matsunami, K; Otsuka, H; Ohta, S; Takeda, Y (2012). "Annonamine, a new aporphine alkaloid from the leaves of Annona muricata". Chemical & Pharmaceutical Bulletin. 60 (2): 257–9. doi:10.1248/cpb.60.257. PMID 22293487.
  2. ^ Moghadamtousi, Soheil; Fadaeinasab, Mehran; Nikzad, Sonia; Mohan, Gokula; Ali, Hapipah; Kadir, Habsah (10 July 2015). "Annona muricata (Annonaceae): A Review of Its Traditional Uses, Isolated Acetogenins and Biological Activities". International Journal of Molecular Sciences. 16 (7): 15625–15658. doi:10.3390/ijms160715625. PMC 4519917. PMID 26184167.


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This page was last edited on 1 December 2023, at 19:33
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