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ADP-sugar diphosphatase

From Wikipedia, the free encyclopedia

In enzymology, an ADP-sugar diphosphatase (EC 3.6.1.21) is an enzyme that catalyzes the chemical reaction

ADP-sugar + H2O AMP + alpha-D-aldose 1-phosphate

Thus, the two substrates of this enzyme are ADP-sugar and H2O, whereas its two products are AMP and alpha-D-aldose 1-phosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides in phosphorus-containing anhydrides. The systematic name of this enzyme class is ADP-sugar sugarphosphohydrolase. Other names in common use include ADP-sugar pyrophosphatase, and adenosine diphosphosugar pyrophosphatase. This enzyme participates in 3 metabolic pathways: fructose and mannose metabolism, purine metabolism, and starch and sucrose metabolism.

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Transcription

References

  • Rodriguez P, Bass ST, Hansen RG (1968). "A pyrophosphatase from mammalian tissues specific for derivatives of ADP". Biochim. Biophys. Acta. 167 (1): 199–201. doi:10.1016/0005-2744(68)90294-5. PMID 5686292.


This page was last edited on 26 August 2023, at 13:00
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