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23S rRNA (guanine2445-N2)-methyltransferase

From Wikipedia, the free encyclopedia

23S rRNA (guanine2445-N2)-methyltransferase (EC 2.1.1.173, ycbY (gene), rlmL (gene)) is an enzyme with systematic name S-adenosyl-L-methionine:23S rRNA (guanine2445-N2)-methyltransferase.[1] This enzyme catalyses the following chemical reaction

S-adenosyl-L-methionine + guanine2445 in 23S rRNA S-adenosyl-L-homocysteine + N2-methylguanine2445 in 23S rRNA

The enzyme methylates 23S rRNA in vitro.

References

  1. ^ Lesnyak DV, Sergiev PV, Bogdanov AA, Dontsova OA (November 2006). "Identification of Escherichia coli m2G methyltransferases: I. the ycbY gene encodes a methyltransferase specific for G2445 of the 23 S rRNA". Journal of Molecular Biology. 364 (1): 20–5. doi:10.1016/j.jmb.2006.09.009. PMID 17010378.

External links

This page was last edited on 26 August 2023, at 12:52
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