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Zinc finger and scan domain containing 4

From Wikipedia, the free encyclopedia

ZSCAN4
Identifiers
AliasesZSCAN4, ZNF494, zinc finger and SCAN domain containing 4
External IDsOMIM: 613419; MGI: 3708485; HomoloGene: 138332; GeneCards: ZSCAN4; OMA:ZSCAN4 - orthologs
Orthologs
SpeciesHumanMouse
Entrez

201516

665902

Ensembl

ENSG00000180532

ENSMUSG00000070828

UniProt

Q8NAM6

Q3URS2

RefSeq (mRNA)

NM_152677
NM_001384833

NM_001110316

RefSeq (protein)

NP_689890

NP_001103786

Location (UCSC)Chr 19: 57.67 – 57.68 MbChr 7: 11.13 – 11.14 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Zinc finger and SCAN domain containing 4 is a protein that in humans is encoded by the ZSCAN4 gene. [5]

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Transcription

Function

The ZSCAN4 gene encodes a protein involved in telomere maintenance and with a key role in the critical feature of mouse embryonic stem cells, namely, defying cellular senescence and maintaining normal karyotype for many cell divisions in culture.[6]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000180532 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000070828 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Zinc finger and SCAN domain containing 4". Retrieved 2017-06-05.
  6. ^ Ko, Minoru S. H.; Wersto, Robert P.; Indig, Fred E.; Yang, Hsih-Te; Hoang, Hien G.; Carole A. Stagg; Lee, Sung-Lim; Thomas, Marshall; Nishiyama, Akira (April 2010). "Zscan4 regulates telomere elongation and genomic stability in ES cells". Nature. 464 (7290): 858–863. Bibcode:2010Natur.464..858Z. doi:10.1038/nature08882. ISSN 1476-4687. PMC 2851843. PMID 20336070.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


Stub icon

This article on a gene on human chromosome 19 is a stub. You can help Wikipedia by expanding it.

This page was last edited on 27 July 2023, at 16:09
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