UBA5

UBA5

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
3GUC, 3H8V, 5HKH

Identifiers

Aliases

UBA5, THIFP1, UBE1DC1, ubiquitin like modifier activating enzyme 5, SCAR24, EIEE44, DEE44

External IDs

OMIM: 610552 MGI: 1913913 HomoloGene: 11738 GeneCards: UBA5

Gene location (Human)

Chr.	Chromosome 3 (human)^[1]

Band	3q22.1	Start	132,654,446 bp^[1]
Band	3q22.1	End	132,679,794 bp^[1]

Gene location (Mouse)

Chr.	Chromosome 9 (mouse)^[2]

Band	9\|9 F1	Start	103,923,798 bp^[2]
Band	9\|9 F1	End	103,940,333 bp^[2]

RNA expression pattern

Bgee

Human

Mouse (ortholog)

Top expressed in

body of pancreas

right adrenal gland

left adrenal gland

parotid gland

anterior pituitary

Achilles tendon

minor salivary gland

secondary oocyte

right uterine tube

left lobe of thyroid gland

Top expressed in

lacrimal gland

parotid gland

seminal vesicula

fossa

islet of Langerhans

supraoptic nucleus

facial motor nucleus

substantia nigra

median eminence

condyle

More reference expression data

BioGPS


More reference expression data

Gene ontology
Molecular function	nucleotide binding protein binding ubiquitin-like modifier activating enzyme activity ATP binding metal ion binding UFM1 activating enzyme activity
Cellular component	cytoplasm intracellular membrane-bounded organelle nucleus cytosol Golgi apparatus
Biological process	regulation of intracellular estrogen receptor signaling pathway protein K69-linked ufmylation response to endoplasmic reticulum stress protein ufmylation neuromuscular process protein modification by small protein conjugation
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse

Entrez


79876


66663

Ensembl


ENSG00000081307


ENSMUSG00000032557

UniProt


Q9GZZ9


Q8VE47

RefSeq (mRNA)


NM_024818 NM_198329 NM_001320210 NM_001321238 NM_001321239


NM_025692

RefSeq (protein)


NP_001307139 NP_001308167 NP_001308168 NP_079094 NP_938143


NP_079968

Location (UCSC)

Chr 3: 132.65 – 132.68 Mb

Chr 9: 103.92 – 103.94 Mb

PubMed search

^[3]

^[4]

Wikidata

View/Edit Human

View/Edit Mouse

Ubiquitin-like modifier-activating enzyme 5 is a protein that in humans is encoded by the UBA5 gene.^[5]^[6]^[7]

This gene encodes a member of the E1-like activating enzyme family. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.^[7]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000081307 - Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000032557 - Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Bocher M, Blocker H, Bauersachs S, Blum H, Lauber J, Dusterhoft A, Beyer A, Kohrer K, Strack N, Mewes HW, Ottenwalder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (Mar 2001). "Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
^ Komatsu M, Chiba T, Tatsumi K, Iemura S, Tanida I, Okazaki N, Ueno T, Kominami E, Natsume T, Tanaka K (May 2004). "A novel protein-conjugating system for Ufm1, a ubiquitin-fold modifier". EMBO J. 23 (9): 1977–86. doi:10.1038/sj.emboj.7600205. PMC 404325. PMID 15071506.
^ ^a ^b "Entrez Gene: UBE1DC1 ubiquitin-activating enzyme E1-domain containing 1".

External links

Overview of all the structural information available in the PDB for UniProt: Q9GZZ9 (Human Ubiquitin-like modifier-activating enzyme 5 (UBE1DC1)) at the PDBe-KB.

This article on a gene on human chromosome 3 is a stub. You can help Wikipedia by expanding it.

This page was last edited on 3 March 2023, at 22:25

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References

Further reading

External links