SLC22A14

SLC22A14
Identifiers
Aliases	SLC22A14, OCTL2, OCTL4, ORCTL4, solute carrier family 22 member 14
External IDs	OMIM: 604048 MGI: 2685974 HomoloGene: 3530 GeneCards: SLC22A14
Gene location (Human) Chr. Chromosome 3 (human)[1] Band 3p22.2 Start 38,282,294 bp[1] End 38,318,575 bp[1]
Gene location (Mouse) Chr. Chromosome 9 (mouse)[2] Band 9|9 F3 Start 118,998,523 bp[2] End 119,194,619 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in pancreatic ductal cell tibialis anterior muscle deltoid muscle sperm superior frontal gyrus occipital lobe rhombencephalon metencephalon cerebellum metanephros Top expressed in spermatid seminiferous tubule spermatocyte proximal tubule yolk sac kidney white adipose tissue spleen islet of Langerhans respiratory system More reference expression data BioGPS n/a
Gene ontology Molecular function organic cation transmembrane transporter activity transmembrane transporter activity inorganic anion exchanger activity sodium-independent organic anion transmembrane transporter activity Cellular component integral component of membrane integral component of plasma membrane membrane Biological process organic cation transport transmembrane transport inorganic anion transport sodium-independent organic anion transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 9389 382113 Ensembl ENSG00000144671 ENSMUSG00000070280 UniProt Q9Y267 Q497L9 RefSeq (mRNA) NM_004803 NM_001320033 NM_001037749 RefSeq (protein) NP_001306962 NP_004794 NP_001032838 Location (UCSC) Chr 3: 38.28 – 38.32 Mb Chr 9: 119 – 119.19 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Solute carrier family 22 member 14 is a protein that in humans is encoded by the SLC22A14 gene.^[5]

Function

This gene encodes a member of the organic-cation transporter family. It is located in a gene cluster with another member of the family, organic cation transporter like 3. The encoded protein is a transmembrane protein which is thought to transport small molecules and since this protein is conserved among several species, it is suggested to have a fundamental role in mammalian systems. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016].

References

Further reading

This article on a gene on human chromosome 3 is a stub. You can help Wikipedia by expanding it.

• v
• t
• e

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This page was last edited on 23 January 2021, at 23:18