Retinoid receptors are nuclear receptors (a class of proteins) that bind to retinoids. When bound to a retinoid, they act as transcription factors, altering the expression of genes with corresponding response elements. Significant age-related declines in the levels of retinoid receptors in the forebrains of rats have been reversed by supplementation with the omega-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), which can restore neurogenesis.[1]
Subtypes include:
- Retinoic acid receptors (RARs)
- Retinoid X receptors (RXRs)
- RAR-related orphan receptors (RORs)
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This page was last edited on 13 October 2022, at 20:18