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Pinaverium bromide

From Wikipedia, the free encyclopedia

Pinaverium bromide
Clinical data
ATC code
Identifiers
  • 4-[(2-Bromo-4,5-dimethoxyphenyl)methyl]-4-[2-[2-(6,6-dimethyl-4-bicyclo[3.1.1]heptanyl)ethoxy]ethyl]morpholin-4-ium bromide
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
Chemical and physical data
FormulaC26H41Br2NO4
Molar mass591.425 g·mol−1
3D model (JSmol)
  • CC1(C2CCC(C1C2)CCOCC[N+]3(CCOCC3)Cc4cc(c(cc4Br)OC)OC)C.[Br-]
  • InChI=1S/C26H41BrNO4.BrH/c1-26(2)21-6-5-19(22(26)16-21)7-11-31-12-8-28(9-13-32-14-10-28)18-20-15-24(29-3)25(30-4)17-23(20)27;/h15,17,19,21-22H,5-14,16,18H2,1-4H3;1H/q+1;/p-1 ☒N
  • Key:IKGXLCMLVINENI-UHFFFAOYSA-M ☒N
 ☒NcheckY (what is this?)  (verify)

Pinaverium bromide (INN) is a medication used for functional gastrointestinal disorders. It belongs to a drug group called antispasmodics and acts as a calcium channel blocker in helping to restore the normal contraction process of the bowel. It is most effective when taken for a full course of treatment and is not designed for immediate symptom relief or sporadic, intermittent use.[1]

Pinaverium bromide was first registered in 1975 by Solvay Pharmaceuticals (now a division of Abbott Laboratories), and marketed globally using the brand names Dicetel and Eldicet. Generic pinaverium is available in South Korea under a trade name of Disten[2] and in Argentina as Nulite.[3]

YouTube Encyclopedic

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  • Pinaverium (Dicetel) - Uses, Dosing, Side Effects | Pharmacist Review
  • Eldicet 50mg Pinaverium Bromide Uses, Price, Side Effects इरिटेबल बॉवेल सिंड्रोम का इलाज
  • What does otilonium bromide mean?

Transcription

Indications

It is indicated for the treatment and relief of symptoms associated with irritable bowel syndrome (IBS) including abdominal pain, bowel disturbances and intestinal discomfort; and treatment of symptoms related to functional disorders of biliary tract.[4]

References

  1. ^ "Trimebutine Maleate and Pinaverium Bromide for Irritable Bowel Syndrome: A Review of the Clinical Effectiveness, Safety and Guidelines [Internet].". CADTH Rapid Response Reports. Ottawa (ON): Canadian Agency for Drugs and Technologies in Health. November 2015. PMID 26985535.
  2. ^ "Drug/Drug Information: Disten Tablet". KMLE (in Korean).
  3. ^ "NULITE". Laboratorio Dominguez.
  4. ^ Abbott Laboratories (Feb 2012). Dicetel Product Insert/Information Malaysia.
This page was last edited on 4 March 2024, at 19:25
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