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Orobol

From Wikipedia, the free encyclopedia

Orobol
Orborol molecule
Names
IUPAC name
3′,4′,5,7-Tetrahydroxyisoflavone
Systematic IUPAC name
3-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-4H-1-benzopyran-4-one
Other names
Isoluteolin
Santol
5,7,3',4'-Tetrahydroxyisoflavone
Identifiers
3D model (JSmol)
292790
ChEBI
ChemSpider
MeSH D011794
UNII
  • InChI=1S/C15H10O6/c16-8-4-12(19)14-13(5-8)21-6-9(15(14)20)7-1-2-10(17)11(18)3-7/h1-6,16-19H ☒N
    Key: IOYHCQBYQJQBSK-UHFFFAOYSA-N ☒N
  • InChI=1/C15H10O6/c16-8-4-12(19)14-13(5-8)21-6-9(15(14)20)7-1-2-10(17)11(18)3-7/h1-6,16-19H
    Key: IOYHCQBYQJQBSK-UHFFFAOYAR
  • C1=CC(=C(C=C1C2=COC3=CC(=CC(=C3C2=O)O)O)O)O
Properties
C15H10O6
Molar mass 286.23 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)

Orobol is one of several known isoflavones. It can be isolated from Aspergillus niger or Streptomyces neyagawaensis. It is a potent inhibitor of Phosphoinositide 3-kinase.[1][2]

References

  1. ^ Orobol on curehunter.com
  2. ^ "Isoflavonoids, genistein, psi-tectorigenin, and orobol, increase cytoplasmic free calcium in isolated rat hepatocytes. Tomonaga, T : Mine, T : Kojima, I : Taira, M : Hayashi, H : Isono, K, 1992". Archived from the original on 2009-07-19. Retrieved 2009-09-15.
This page was last edited on 6 May 2023, at 03:40
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