Michelin tire baby syndrome (also known as Kunze–Riehm syndrome[1] and "folded skin with scarring"[2]: 625 ), is a condition occurring in babies that is characterized by multiple, symmetric, circular skin creases, or bands, on the forearms, lower legs, and often the neck that are present at birth. The creases disappear later in life. They are reminiscent of those of Bibendum, the mascot of the tire manufacturer Michelin, hence the name of the syndrome. Associated abnormalities vary and may include facial dysmorphism, upslanting palpebral fissures, hypertelorism, cleft palate, genital anomalies, mild developmental delay, ureterocele, smooth muscle hamartoma, nevus lipomatosus, Laron syndrome (dwarfism with high growth hormone and low somatomedin activity), and other defects.
It was originally described by Ross in 1969.[3]
See also
Notes
- ^ Ramphul, Kamleshun; Mejias, Stephanie G; Ramphul-Sicharam, Yogeshwaree (2018). "A Rare Case of Michelin Tire Baby Syndrome in a Newborn". Cureus. 10 (2): e2222. doi:10.7759/cureus.2222. ISSN 2168-8184. PMC 5914916. PMID 29696100.
- ^ James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. ISBN 0-7216-2921-0.
- ^ Ross CM (September 1969). "Generalized folded skin with an underlying lipomatous nevus. "The Michelin Tire baby"". Arch Dermatol. 100 (3): 320–3. doi:10.1001/archderm.100.3.320. PMID 4980758.[permanent dead link]
References
- Bass HN, Caldwell S, Brooks BS (February 1993). "Michelin tire baby syndrome: familial constriction bands during infancy and early childhood in four generations". Am J Med Genet. 45 (3): 370–2. doi:10.1002/ajmg.1320450318. PMID 8434626.
- Schnur RE, Herzberg AJ, Spinner N, et al. (February 1993). "Variability in the Michelin tire syndrome. A child with multiple anomalies, smooth muscle hamartoma, and familial paracentric inversion of chromosome 7q". J Am Acad Dermatol. 28 (2 Pt 2): 364–70. doi:10.1016/0190-9622(93)70056-Y. PMID 8436660.
- Schnur RE, Zackai EH (March 1997). "Circumferential ringed creases ('Michelin tire babies') with specific histologic findings and/or karyotype abnormalities: clues to molecular pathogenesis?". Am J Med Genet. 69 (2): 221. doi:10.1002/(SICI)1096-8628(19970317)69:2<221::AID-AJMG22>3.0.CO;2-M. PMID 9056567.
- Pivnick EK, Wilroy RS, Martens PR, Teather TC, Hashimoto K (April 1996). "Hypertrichosis, pigmentary retinopathy, and facial anomalies: a new syndrome?". Am J Med Genet. 62 (4): 386–90. doi:10.1002/(SICI)1096-8628(19960424)62:4<386::AID-AJMG11>3.0.CO;2-K. PMID 8723069.
- Oku T, Iwasaki K, Fujita H (November 1993). "Folded skin with an underlying cutaneous smooth muscle hamartoma". Br J Dermatol. 129 (5): 606–8. doi:10.1111/j.1365-2133.1993.tb00495.x. PMID 8251362. S2CID 34499359.
External links
This page was last edited on 6 January 2024, at 21:06