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From Wikipedia, the free encyclopedia

Jean M.J. Fréchet (born August 1944) is a French-American chemist and professor emeritus at the University of California, Berkeley. He is best known for his work on polymers including polymer-supported chemistry, chemically amplified photoresists, dendrimers, macroporous separation media, and polymers for therapeutics. Ranked among the top 10 chemists in 2021,[2] he has authored nearly 900 scientific paper and 200 patents including 96 US patents.[3] His research areas include organic synthesis and polymer chemistry applied to nanoscience and nanotechnology with emphasis on the design, fundamental understanding, synthesis, and applications of functional macromolecules.

Fréchet is an elected fellow of the American Association for the Advancement of Science, the American Chemical Society, and the American Academy of Arts and Sciences, and an elected member of the US National Academy of Sciences, the US National Academy of Engineering, and the Academy of Europe (Academia Europaea).

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  • 2013 (29th) Japan Prize: Prof. Willson & Prof. Fréchet
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2013 (29th) Japan Prize Laureate in the field of Materials and Production Grant Willson, Ph.D. (United States) Jean Fréchet, Ph.D. (United States) Prof. Grant Willson was born in 1939 in California, United Sates. Since he was a child, Prof. Willson was a passionate reader of science magazines. After graduating from high school, he took up an internship at a local chemical manufacturer. Thereafter, he advanced to University of California, Berkeley to study organic chemistry. Beside university studies, he was also passionate about yacht racing. After graduation, he joined IBM, which at the time had just entered the small computer market. Prof. Jean Fréchet was born in 1944 in Bourgogne, France. Influenced by his father who was a chemist, Prof. Fréchet had an aspiration to become a chemist as a child. He advanced to the Institut de Chimie et Physique Industrielles in Lyon and pursued industrial chemistry. After graduating, he moved to the United Sates and earned a PhD in Polymer Chemistry from the State University of New York, and a PhD in Organic Chemistry from Syracuse University. Thereafter, he became an Associate Professor of Chemistry at the University of Ottawa where he began his own research as a chemist. During the 1980s, IBM, where Prof. Willson worked, was leading the world in the production of semiconductor devices. Moore's law announced in 1965 predicted that "the number of transistors on integrated circuits doubles approximately every two years". As predicted, the semiconductor industry was urgently pursuing higher integration. In order to create the minute circuits of a semiconductor, a coating called resist must first be formed on the surface of the silicon wafer. It is then exposed to light, such as ultraviolet light, through a photomask which causes the exposed area to chemically change by photochemical reaction. Through this technique, minute circuit patterns can be printed as positive or negative image. During the manufacturing process, shortening the wavelength of ultraviolet light during exposure results in higher resolution but it also lowers exposure sensitivity. This problem becomes an obstacle when trying to draw minute circuits. So there was a huge interest in improving the resist's exposure sensitivity. At the time, Prof. Fréchet, who came to IBM on a sabbatical leave from the University of Ottawa, proposed a solution for this problem. This was the "chemically amplified resist" approach. First, light exposure generates catalyst inside the resist. Prof. Fréchet and Willson thought that by having the catalyst trigger a chain reaction inside the resist, the nature of all the resist polymers could be changed at once with little exposure. Hence, enough exposure sensitivity could be achieved with short wavelength light. Even after Prof. Fréchet returned to the University of Ottawa, their collaborative research continued. Major progress came when Dr. Ito, who was at the time studying polysaccharide synthesis at the State University of New York, joined their research team. In 1985 after numerous trial and errors, this research team led by Prof. Willson succeeded in developing a stable resist polymer material. From thereafter, Prof. Willson traveled back-and-forth between the research laboratory in Silicon Valley and the factory in Vermont to bring the memory chip manufacturing to the level of mass production. Finally, chemically amplified resist went from being a laboratory experiment to a technology supporting the manufacturing of memory chips with the largest memory capacity at the time. Seeing this, Prof. Willson strongly felt that in the future, this kind of resist will go on to be used to make electronic devices around the world. Behind the research careers of both professors, there was the heartwarming support of their families. After Prof. Willson married his wife Deborah, they were blessed with two sons. Even though Prof. Willson would often be away from home on long business trips, his wife always gave him utmost support with a warm smile. Prof. Fréchet met his wife Janet during his university years and they were married in 1971. They were blessed with two sons. For Prof. Fréchet who is always busy, his family gave him great comfort and support. The two professors are not only research partners but they have been a close family friends for many years. Dr. Hiroshi Ito, who co-researched with the two professors also shared close relationships in work and private life. Unfortunately, Dr. Ito passed way in 2009 but his contributions to the development of resist materials have been tremendous. Today, the "chemically amplified resist" approach has become a standard in semiconductor manufacturing. Starting with electronic devices we use such as PCs and smartphones, to automobiles, it is used to manufacture microprocessors and memory chips used in a wide range of products. Prof. Willson has been recognized for these achievements and has since received numerous awards. Today, he is a Professor at the University of Texas in Austin where he is devoted to nurturing upcoming researchers. Prof. Fréchet continues to actively interact with many researches and is called to numerous seminars and symposiums. Today, he still leads an active career as the Vice-President for Research at King Abdullah University of Science and Technology. [To young researchers] The path you have chosen is not incorrect. Technology is constantly advancing and the future society that awaits us is beyond our imagination. Only by having a solid education in science, technology, engineering or mathematics, one is able to participate in the creation of future technology. Continue your studies with all your effort and find a chance to take part in research activity as early as you can. [To young researchers] Believe in your self and welcome any challenges you face in work. At the same time, do not forget to enjoy life as well. They should be simultaneously achieved. Happiness in work and family life are the best ingredients for success. Be creative, and have open-minded ideas. Don't hesitate to share your ideas with people more experienced than yourself. Be bold. But most of all, never forget that science is supposed to be fun.

Education and academic career

Fréchet received his first university degree at the Institut de Chimie et Physique Industrielles (now CPE) in Lyon, France, before coming to the US for studies in organic and polymer chemistry under Conrad Schuerch at the State University of New York College of Environmental Science and Forestry, and at Syracuse University   (Ph.D. 1971). He was on the Chemistry Faculty at the University of Ottawa in Canada from 1973 to 1987, when he became the IBM Professor of Polymer Chemistry at Cornell University. In 1997 Fréchet joined Chemistry faculty at the University of California, Berkeley and was named the Henry Rapoport Chair of Organic Chemistry in 2003 and Professor of Chemical and Biological Engineering in 2005. From 2010 to 2019 he served as the first Vice President for Research, then Senior Vice-President for Research, Innovation, and Economic Development at the King Abdullah University of Science and Technology.

Research

Fréchet’s early work focused on polymer-supported chemistry with the first approach to the solid-phase synthesis of oligosaccharides [4] and pioneering work on polymeric reagents and polymer protecting groups.[5] In 1979 Working with C.G. Willson at IBM during a sabbatical leave, he invented chemically amplified photoresists [6][7] for micro and nanofabrication. This widely used patented technology [8] which enables the extreme miniaturization of microelectronic devices is now ubiquitous for the fabrication of the very powerful computing and communication equipment in worldwide use. The addition of photogenerated bases [9] led to additional advances in chemically amplified resists. In 1990 working with Craig Hawker at Cornell, he developed the convergent synthesis of dendrimers [10] as well as approaches to hyperbranched polymers.[11] In 1992, working with F. Svec at Cornell, he reported the first preparation of macroporous polymer monoliths [12] that are now used in a variety of chemical separations. Later work at Berkeley saw the development of polymers and dendrimers as carriers for targeted therapeutics [13] and successful approaches to new organic materials for transistors and solar cells.[14]

Honors and awards

  • 2020 National Academy of Engineering Charles Stark Draper Prize in Engineering [15]
  • 2019 King Faisal International Prize in Chemistry [16]
  • 2013 Japan Prize for the "Development of chemically amplified resist polymer materials for innovative semiconductor manufacturing process"[17][18]
  • 2010 Grand Prix de la Maison de la Chimie (Paris) [19]
  • 2010 Erasmus Medal of the Academia Europaea [20]
  • 2010 Society of Polymer Science of Japan, International Award for the "Development of functional polymers from fundamentals to application"
  • 2010 University of California Department of Chemistry Teaching Award
  • 2010 Fellow of the American Chemical Society
  • 2009 Elected to the Academy of Europe (Academia Europaea)
  • 2009 Nagoya Gold Medal[21]
  • 2009 Arun Guthikonda Memorial Award, Columbia University.
  • 2009 Society of Polymer Science of Japan, International Award for the "Development of functional polymers from fundamentals to applications".
  • 2009 Carothers Award for "Outstanding contributions and advances in industrial applications of chemistry".
  • 2009 Herman Mark Award, American Chemical Society.
  • 2008 D.Sc. (Honoris Causa), University of Liverpool, UK
  • 2007 Dickson Prize in Science, Carnegie Mellon University
  • 2007 Arthur C. Cope Award (American Chemical Society award for outstanding achievement in the field of Organic Chemistry)
  • 2006 Macro Group UK Medal (joint Royal Society for Chemistry and Society of Chemical Industry) for Outstanding Achievement in the field of Macromolecular Chemistry
  • 2005 Esselen Award for Chemistry in the Service of the Public
  • 2005 Chemical Communications 40th Anniversary Award
  • 2004 Docteur de L'Université, Université d'Ottawa, Canada
  • 2003 Henry Rapoport Chair of Organic Chemistry, University of California, Berkeley
  • 2002 Docteur (Honoris Causa), Université de Lyon I, France
  • 2001 American Chemical Society, Salute to Excellence Award
  • 2001 American Chemical Society, A.C. Cope Scholar Award
  • 2000 Elected Fellow of the American Academy of Arts and Sciences
  • 2000 Elected Member of the US National Academy of Engineering
  • 2000 Elected Fellow of the PMSE Division of the American Chemical Society
  • 2000 Elected Fellow of the American Association for the Advancement of Science
  • 2000 Elected Member of the US National Academy of Sciences
  • 2000 American Chemical Society, ACS Award in Polymer Chemistry
  • 2000 Myron L. Bender & Muriel S. Bender Distinguished Summer Lectureship
  • 1999 Society of Imaging Science and Technology, Kosar Memorial Award
  • 1996 American Chemical Society, ACS Award in Applied Polymer Science
  • 1995 Peter J. Debye Chair of Chemistry, Cornell University, NY
  • 1994 American Chemical Society, Cooperative Research Award in Polymer Science
  • 1987 IBM Professor of Polymer Chemistry
  • 1986 American Chemical Society, Doolittle Award in Polymer Materials Science & Engineering
  • 1986 Polymer Society of Japan Lecture Award
  • 1983 IUPAC Canadian National Committee Award

References

  1. ^ WorldCat. Accessed: January 31, 2013.
  2. ^ "World's Best Chemistry Scientists: H-Index Chemistry Science Ranking".
  3. ^ "Jean M. J. Frechet Inventions, Patents and Patent Applications – Justia Patents Search".
  4. ^ Fréchet, J.M.J.; Schuerch, C. Solid-Phase Synthesis of Oligosaccharides. III. Preparation of Some Derivatives of di- and tri- saccharides via a simple Alcoholysis Reaction. Carbohyd. Res., 1972, 22, 399–412
  5. ^ Fréchet, J.M.J. Synthesis and Applications of Organic Polymers as Supports and Protecting Groups. Tetrahedron, 1981, 37, 663–83
  6. ^ Fréchet, J.M.J.; Ito, H.; Willson, C.G. Sensitive Deep UV Resist Incorporating Chemical Amplification. Proceedings Microcircuit Engineering 1982, Grenoble, 260–261
  7. ^ "Patterning the World: The Rise of Chemically Amplified Photoresists". 2 October 2007.
  8. ^ Ito, H., Willson. C.G., Fréchet, J.M.J Positive and Negative Working Resist Compositions with Acid-Generating Photoinitiator and Polymer with Acid-Labile Groups Pendant From Polymer Backbone. US Patent No. 4,491,628 issued January 1, 1985
  9. ^ Frechet, J.M.J. Pure & Appl. Chem., 1992, 64, 1239–1248
  10. ^ Hawker, C.J.; Fréchet, J.M.J. Preparation of Polymers with Controlled Molecular Architecture: A New Convergent Approach to Dendritic Macromolecules. J. Am. Chem. Soc. 1990, 112, 7638–47
  11. ^ Tomalia, D. A.; Fréchet, J.M. J. Discovery of dendrimers and dendritic polymers: a brief historical perspective. 2002, Journal of Polymer Science, Part A: Polymer Chemistry 40, 2719–2728
  12. ^ Svec, F.; Fréchet, J.M.J. Novel continuous rods of macroporous polymer as High-Performance Liquid Chromatography Separation Media. Analytical Chemistry 1992, 64, 820–822
  13. ^ Fox, M.E.; Szoka, F.C.; Fréchet, J.M.J.; Soluble polymer carriers for the treatment of cancer: the importance of molecular architecture. Accounts Chem Res. 2009. 42, 1141–1151
  14. ^ Beaujuge, P.M.; Frechet, J.M.J. Molecular Design and Ordering Effects in pi-Functional Materials for Transistor and Solar Cell Applications – A Perspective. J. Am. Chem. Soc. 2011, 133, 20009-20029
  15. ^ "2020 Charles Stark Draper Prize for Engineering Recipients".
  16. ^ King Faisal International Prize 2019
  17. ^ Tobin, Dave. (2013, January 30). "SUNY ESF alumnus Jean Fréchet wins Japan Prize," Archived 2019-01-10 at the Wayback Machine Syracuse.com. Accessed: January 31, 2013.
  18. ^ "Laureates of the Japan Prize The 2013 (29th) Japan Prize". Japan Prize Foundation. Retrieved 2013-02-13.
  19. ^ "Les anciens lauréats".
  20. ^ "Academy of Europe: Erasmus Medal 2010".
  21. ^ "The Nagoya Medal of Organic Chemistry" (PDF). www.itbm.nagoya-u.ac.jp. Nagoya University. Archived (PDF) from the original on 18 July 2022. Retrieved 27 July 2022.

External links

This page was last edited on 17 March 2024, at 12:57
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