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3-keto-steroid reductase is an enzyme that in humans is encoded by the HSD17B7gene.[5][6][7][8]
The 17-beta-hydroxysteroid dehydrogenase enzyme (EC 1.1.1.62) oxidizes or reduces estrogens and androgens in mammals and regulates the biologic potency of these steroids.[supplied by OMIM][8]
Mendoza-Hernández G, Rendón JL, Díaz-Zagoya JC (1985). "A single step procedure for purification of estradiol 17 beta-dehydrogenase from human placenta". Biochem. Biophys. Res. Commun. 126 (1): 477–81. doi:10.1016/0006-291X(85)90630-8. PMID3855619.
Törn S, Nokelainen P, Kurkela R, et al. (2003). "Production, purification, and functional analysis of recombinant human and mouse 17beta-hydroxysteroid dehydrogenase type 7". Biochem. Biophys. Res. Commun. 305 (1): 37–45. doi:10.1016/S0006-291X(03)00694-6. PMID12732193.
Marijanovic Z, Laubner D, Moller G, et al. (2004). "Closing the gap: identification of human 3-ketosteroid reductase, the last unknown enzyme of mammalian cholesterol biosynthesis". Mol. Endocrinol. 17 (9): 1715–25. doi:10.1210/me.2002-0436. PMID12829805.
Ohnesorg T, Adamski J (2005). "Promoter analyses of human and mouse 17beta-hydroxysteroid dehydrogenase type 7". J. Steroid Biochem. Mol. Biol. 94 (1–3): 259–61. doi:10.1016/j.jsbmb.2005.01.012. PMID15862973. S2CID46113625.
Ohnesorg T, Adamski J (2006). "Analysis of the 5' flanking regions of human and murine HSD17B7: identification of a cholesterol dependent enhancer region". Mol. Cell. Endocrinol. 248 (1–2): 164–7. doi:10.1016/j.mce.2005.10.016. PMID16356630. S2CID8896905.
Smuc T, Pucelj MR, Sinkovec J, et al. (2007). "Expression analysis of the genes involved in estradiol and progesterone action in human ovarian endometriosis". Gynecol. Endocrinol. 23 (2): 105–11. doi:10.1080/09513590601152219. PMID17454161. S2CID41842764.
Guggenberger C, Ilgen D, Adamski J (2007). "Functional analysis of cholesterol biosynthesis by RNA interference". J. Steroid Biochem. Mol. Biol. 104 (3–5): 105–9. doi:10.1016/j.jsbmb.2007.03.001. PMID17498944. S2CID20838858.
This page was last edited on 2 April 2024, at 15:09