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Glucametacin

From Wikipedia, the free encyclopedia

Glucametacin
Clinical data
Trade namesTeoremac
Other namesIndometacin glucosamide
Identifiers
  • 2-[1-(4-Chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]-N-[(2R,3R,4S,5R)-3,4,5,6-tetrahydroxy-1-oxohexan-2-yl]acetamide
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.052.640 Edit this at Wikidata
Chemical and physical data
FormulaC25H27ClN2O8
Molar mass518.95 g·mol−1

Glucametacin is a non-steroidal anti-inflammatory drug used for the treatment of mild or moderate pain associated with rheumatoid arthritis, osteoarthritis, and other rheumatological disorders.[1] It has analgesic and anti-inflammatory effects.[1][2][3]

Glucametacin is an amide of indometacin with glucosamine.

References

  1. ^ a b Capelli L, Chianese V, La Montagna G, Giordano M (1981). "Further studies on glucametacin in rheumatoid arthritis and in other chronic types of rheumatism". Current Medical Research and Opinion. 7 (4): 227–233. doi:10.1185/03007998109114267. PMID 6971729.
  2. ^ Akatsu T, Catanzaro Guimarães SA (1986). "Comparative effects of non-steroidal anti-inflammatory drugs, mefenamic acid, metiazinic acid and glucametacin on the inflammatory response induced by subcutaneous implantation of human dental plaque and on the mitotic activity of isoproterenol-stimulated parotid glands of rats". Cellular and Molecular Biology. 32 (5): 619–626. PMID 3779763.
  3. ^ Ibba G, Uras R, Perpignano G (1983). "Double-blind comparison of glucametacin and ketoprofen in chronic arthropathies". Current Medical Research and Opinion. 8 (5): 321–326. doi:10.1185/03007998309112391. PMID 6340973.


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This page was last edited on 27 October 2023, at 00:14
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