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Summary
| Description |
Prototypic Phlebovirus virion and genome organization. (A) Virus particles contain the pseudocircularized tripartite single-stranded RNA genome, packaged into virus-sense RNPs (vRNPs) by nucleocapsid protein N and associated with the viral RNA-dependent RNA polymerase (RdRp) L, within a lipid envelope covered by heterodimers of glycoproteins Gn and Gc; and (B) the three viral genome segments large (L), medium (M) (both being purely negative-sense), and small (S) (ambisense) code for the structural proteins L, the Gn and Gc, and N, respectively. Viral mRNAs contain a 5′-cap (dot) and short heterogenous host-derived sequences. mRNAs transcribed from genomic RNAs are shown as grey arrows. The nonstructural protein NSs mRNA (green arrow) is synthesized from antigenomic RNA (two-colored arrow). Dipteran-borne phleboviruses also encode a nonstructural protein on the M segment (NSm). |
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| Date | |||
| Source | Fig. 1 at https://www.mdpi.com/1999-4915/8/6/174/htm - Phleboviruses and the Type I Interferon Response. In: MDPI Viruses 2016, 8(6), 174; doi:10.3390/v8060174. | ||
| Author | Jennifer Deborah Wuerth and Friedemann Weber | ||
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 08:48, 7 September 2020 | | 3,535 × 1,037 (632 KB) | Guest2625 | Uploaded a work by https://www.mdpi.com/1999-4915/8/6/174/htm from Jennifer Deborah Wuerth and Friedemann Weber with UploadWizard |
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