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Epipodophyllotoxin

From Wikipedia, the free encyclopedia

Etoposide, an epipodophyllotoxin

Epipodophyllotoxins are substances naturally occurring in the root of American Mayapple plant (Podophyllum peltatum).

Some epipodophyllotoxin derivatives are currently used in the treatment of cancer. These include etoposide and teniposide. They act as anti-cancer drugs by inhibiting topoisomerase II.[1]

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  • Topoisomerase 1 and 2

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See also

References

  1. ^ Takimoto CH, Calvo E. "Principles of Oncologic Pharmacotherapy" Archived 2009-05-15 at the Wayback Machine in Pazdur R, Wagman LD, Camphausen KA, Hoskins WJ (Eds) Cancer Management: A Multidisciplinary Approach Archived 2013-10-04 at the Wayback Machine. 11 ed. 2008.
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This page was last edited on 11 March 2024, at 18:17
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