To install click the Add extension button. That's it.

The source code for the WIKI 2 extension is being checked by specialists of the Mozilla Foundation, Google, and Apple. You could also do it yourself at any point in time.

4,5
Kelly Slayton
Congratulations on this excellent venture… what a great idea!
Alexander Grigorievskiy
I use WIKI 2 every day and almost forgot how the original Wikipedia looks like.
Live Statistics
English Articles
Improved in 24 Hours
Added in 24 Hours
Languages
Recent
Show all languages
What we do. Every page goes through several hundred of perfecting techniques; in live mode. Quite the same Wikipedia. Just better.
.
Leo
Newton
Brights
Milds

Dibenzoylhydrazine

From Wikipedia, the free encyclopedia

Dibenzoylhydrazine
Names
Preferred IUPAC name
N′-Benzoylbenzohydrazide
Other names
1,2-Dibenzoylhydrazine
Identifiers
3D model (JSmol)
523810
ChEBI
ChEMBL
ChemSpider
ECHA InfoCard 100.011.209 Edit this at Wikidata
EC Number
  • 212-329-9
281733
UNII
  • InChI=1S/C14H12N2O2/c17-13(11-7-3-1-4-8-11)15-16-14(18)12-9-5-2-6-10-12/h1-10H,(H,15,17)(H,16,18)
    Key: GRRIYLZJLGTQJX-UHFFFAOYSA-N
  • C1=CC=C(C=C1)C(=O)NNC(=O)C2=CC=CC=C2
Properties
C14H12N2O2
Molar mass 240.262 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Dibenzoylhydrazine (DBH) is a synthetic chemical compound with the chemical formulation C14H12N2O2.

Insecticidal Derivatives

Appropriately substituted dibenzoyl hydrazines show insecticidal activity.[1] This class, usually known as bisacylhydrazines (BAHs), does not immediately kill the insect, but produces premature unsuccessful moulting, which then causes the death of the insect. BAHs thus belong to the class of insect growth regulators.

The insecticidal activity of RH-5849 was discovered serendipitously in 1984 at Rohm and Haas, who later commercialised tebufenozide methoxyfenozide, and halofenozide. Later other companies commercialised chromafenozide and fufenozide. The EPA removed halofenozide from the market in 2012 on the request of the manufacturer.[1] BAHs were estimated to account for ca 1% of the 18.4 billion dollar 2018 global pesticide market.[2]

BAHs are used against lepidoptera, with some applications against coleopteran and dipteran pests.[1] Many plants produce chemicals (phytoecdysteroids) which use this mode of action to kill insects.

BAHs act by agonising the ecdysone receptor. Crystal structures of BAHs bound to the ecdysone receptor were obtained.[1]

BAHs show low mamalian and environmental toxicity. Methoxyfenozide was given a presidential green chemistry award in 1998. Both tebufenozide and methoxyfenozide were registered by the EPA under its Reduced Risk Pesticide Program.[1]


Tebufenozide, methoxyfenozide and halofenozide are classed as commercial DBHs.[3]

In 2013, a compound of the substance was tested with promising results against larvae of Anopheles gambiae, the major vector for human malaria.[3]

References

  1. ^ a b c d e Jeschke, Peter; Witschel, Matthias; Krämer, Wolfgang; Schirmer, Ulrich (2019). "Chapter 29.1. Insect Molting and Metamorphosis". Modern Crop Protection Compounds. Wiley. pp. 1013–1049. doi:10.1002/9783527699261.ch29. ISBN 9783527699261.
  2. ^ Sparks, Thomas C. (14 February 2024). "Insecticide mixtures—uses, benefits and considerations". Pest Management Science – via Wiley.
  3. ^ a b "A new dibenzoylhydrazine with insecticidal activity against Anopheles mosquito larvae", Pest Manag Sci. 2013 Jul;69(7):827-33. doi: 10.1002/ps.3441
This page was last edited on 15 May 2024, at 16:07
Basis of this page is in Wikipedia. Text is available under the CC BY-SA 3.0 Unported License. Non-text media are available under their specified licenses. Wikipedia® is a registered trademark of the Wikimedia Foundation, Inc. WIKI 2 is an independent company and has no affiliation with Wikimedia Foundation.