CAMK1G (gene)

CAMK1G

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
2JAM

Identifiers

Aliases

CAMK1G, CLICK3, CLICKIII, VWS1, dJ272L16.1, calcium/calmodulin dependent protein kinase IG

External IDs

OMIM: 614994; MGI: 2388073; HomoloGene: 48706; GeneCards: CAMK1G; OMA:CAMK1G - orthologs

Gene location (Human)

Chr.	Chromosome 1 (human)^[1]

Band	1q32.2	Start	209,583,714 bp^[1]
Band	1q32.2	End	209,613,939 bp^[1]

Gene location (Mouse)

Chr.	Chromosome 1 (mouse)^[2]

Band	1 H6\|1 97.74 cM	Start	193,028,654 bp^[2]
Band	1 H6\|1 97.74 cM	End	193,052,606 bp^[2]

RNA expression pattern

Bgee

Human

Mouse (ortholog)

Top expressed in

frontal pole

Brodmann area 10

Brodmann area 9

cingulate gyrus

nucleus accumbens

middle frontal gyrus

Region I of hippocampus proper

superior frontal gyrus

putamen

caudate nucleus

Top expressed in

ventromedial nucleus

superior frontal gyrus

visual cortex

olfactory tubercle

pontine nuclei

primary motor cortex

nucleus accumbens

medial ganglionic eminence

subiculum

prefrontal cortex

More reference expression data

BioGPS

n/a

Gene ontology
Molecular function	transferase activity nucleotide binding protein kinase activity protein serine/threonine kinase activity catalytic activity ATP binding kinase activity calmodulin-dependent protein kinase activity calmodulin binding
Cellular component	cytoplasm calcium- and calmodulin-dependent protein kinase complex neuron projection Golgi membrane plasma membrane Golgi apparatus membrane endomembrane system intracellular anatomical structure
Biological process	protein phosphorylation metabolism phosphorylation peptidyl-serine phosphorylation peptidyl-threonine phosphorylation intracellular signal transduction
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse

Entrez


57172


215303

Ensembl


ENSG00000008118


ENSMUSG00000016179

UniProt


Q96NX5


Q91VB2

RefSeq (mRNA)


NM_020439


NM_144817

RefSeq (protein)


NP_065172


NP_659066

Location (UCSC)

Chr 1: 209.58 – 209.61 Mb

Chr 1: 193.03 – 193.05 Mb

PubMed search

^[3]

^[4]

Wikidata

View/Edit Human

View/Edit Mouse

Calcium/calmodulin dependent protein kinase IG is a protein that in humans is encoded by the CAMK1G gene. ^[5]

Function

This gene encodes a protein similar to calcium/calmodulin dependent protein kinase, however, its exact function is not known. [provided by RefSeq, Jul 2008].

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000008118 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000016179 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: Calcium/calmodulin dependent protein kinase IG". Retrieved 2018-08-28.

Takemoto-Kimura S, Terai H, Takamoto M, Ohmae S, Kikumura S, Segi E, Arakawa Y, Furuyashiki T, Narumiya S, Bito H (May 2003). "Molecular cloning and characterization of CLICK-III/CaMKIgamma, a novel membrane-anchored neuronal Ca2+/calmodulin-dependent protein kinase (CaMK)". J. Biol. Chem. 278 (20): 18597–605. doi:10.1074/jbc.M300578200. PMID 12637513.
Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt TR, Pallas J, Lovering R, Li K, Casas JP, Sofat R, Kumari M, Rodriguez S, Johnson T, Newhouse SJ, Dominiczak A, Samani NJ, Caulfield M, Sever P, Stanton A, Shields DC, Padmanabhan S, Melander O, Hastie C, Delles C, Ebrahim S, Marmot MG, Smith GD, Lawlor DA, Munroe PB, Day IN, Kivimaki M, Whittaker J, Humphries SE, Hingorani AD (November 2009). "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip". Am. J. Hum. Genet. 85 (5): 628–42. doi:10.1016/j.ajhg.2009.10.014. PMC 2775832. PMID 19913121.
Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B, Yusuf S, Gerstein HC, Engert JC, Anand S (October 2010). "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study". Diabetes Care. 33 (10): 2250–3. doi:10.2337/dc10-0452. PMC 2945168. PMID 20628086.
Pang ZP, Xu W, Cao P, Südhof TC (October 2010). "Calmodulin suppresses synaptotagmin-2 transcription in cortical neurons". J. Biol. Chem. 285 (44): 33930–9. doi:10.1074/jbc.M110.150151. PMC 2962493. PMID 20729199.
Deng M, Wei L, Zuo X, Tian Y, Xie F, Hu P, Zhu C, Yu F, Meng Y, Wang H, Zhang F, Ma H, Ye R, Cheng H, Du J, Dong W, Zhou S, Wang C, Wang Y, Wang J, Chen X, Sun Z, Zhou N, Jiang Y, Liu X, Li X, Zhang N, Liu N, Guan Y, Han Y, Han Y, Lv X, Fu Y, Yu H, Xi C, Xie D, Zhao Q, Xie P, Wang X, Zhang Z, Shen L, Cui Y, Yin X, Cheng H, Liang B, Zheng X, Lee TM, Chen G, Zhou F, Veldink JH, Robberecht W, Landers JE, Andersen PM, Al-Chalabi A, Shaw C, Liu C, Tang B, Xiao S, Robertson J, Zhang F, van den Berg LH, Sun L, Liu J, Yang S, Ju X, Wang K, Zhang X (June 2013). "Genome-wide association analyses in Han Chinese identify two new susceptibility loci for amyotrophic lateral sclerosis". Nat. Genet. 45 (6): 697–700. doi:10.1038/ng.2627. PMID 23624525. S2CID 7924012.

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This page was last edited on 11 October 2022, at 13:42

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Function

References

Further reading