C6orf89

C6orf89

Identifiers

C6orf89, BRAP, chromosome 6 open reading frame 89, PS1TP5TP1

External IDs

OMIM: 616642 MGI: 2136782 HomoloGene: 12728 GeneCards: C6orf89

Gene location (Human)

Chr.	Chromosome 6 (human)^[1]

Band	6p21.2	Start	36,871,870 bp^[1]
Band	6p21.2	End	36,928,964 bp^[1]

Gene location (Mouse)

Chr.	Chromosome 17 (mouse)^[2]

Band	17\|17 A3.3	Start	29,268,788 bp^[2]
Band	17\|17 A3.3	End	29,314,065 bp^[2]

RNA expression pattern

Bgee

Human

Mouse (ortholog)

Top expressed in

islet of Langerhans

smooth muscle tissue

corpus epididymis

stromal cell of endometrium

internal globus pallidus

nipple

urethra

tibialis anterior muscle

gallbladder

sperm

Top expressed in

retinal pigment epithelium

lacrimal gland

right ventricle

interventricular septum

fossa

aortic valve

left lobe of liver

submandibular gland

proximal tubule

iris

More reference expression data

BioGPS


More reference expression data

Gene ontology
Molecular function	protein binding
Cellular component	integral component of membrane Golgi apparatus Golgi membrane nucleus plasma membrane nucleolus midbody membrane cytoplasm
Biological process	positive regulation of histone deacetylase activity epithelial cell proliferation wound healing positive regulation of cell cycle
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse

Entrez


221477


80748

Ensembl


ENSG00000198663


ENSMUSG00000052712

UniProt


Q6UWU4


Q99KU6

RefSeq (mRNA)


NM_001286635 NM_001286636 NM_001286637 NM_152734


NM_030561

RefSeq (protein)


NP_001273564 NP_001273565 NP_001273566 NP_689947 NP_001273564.1


NP_085038

Location (UCSC)

Chr 6: 36.87 – 36.93 Mb

Chr 17: 29.27 – 29.31 Mb

PubMed search

^[3]

^[4]

Wikidata

View/Edit Human

View/Edit Mouse

Uncharacterized protein C6orf89 is a protein that in humans is encoded by the C6orf89 gene.^[5]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000198663 - Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000052712 - Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: C6orf89 chromosome 6 open reading frame 89".

External links

Human BRAP genome location and BRAP gene details page in the UCSC Genome Browser.
Human C6orf89 genome location and C6orf89 gene details page in the UCSC Genome Browser.

Hartley JL, Temple GF, Brasch MA (Nov 2000). "DNA cloning using in vitro site-specific recombination". Genome Research. 10 (11): 1788–1795. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Böcher M, Blöcker H, Bauersachs S, Blum H, Lauber J, Düsterhöft A, Beyer A, Köhrer K, Strack N, Mewes HW, Ottenwälder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (Mar 2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Research. 11 (3): 422–435. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
Clark HF, Gurney AL, Abaya E, Baker K, Baldwin D, Brush J, Chen J, Chow B, Chui C, Crowley C, Currell B, Deuel B, Dowd P, Eaton D, Foster J, Grimaldi C, Gu Q, Hass PE, Heldens S, Huang A, Kim HS, Klimowski L, Jin Y, Johnson S, Lee J, Lewis L, Liao D, Mark M, Robbie E, Sanchez C, Schoenfeld J, Seshagiri S, Simmons L, Singh J, Smith V, Stinson J, Vagts A, Vandlen R, Watanabe C, Wieand D, Woods K, Xie MH, Yansura D, Yi S, Yu G, Yuan J, Zhang M, Zhang Z, Goddard A, Wood WI, Godowski P, Gray A (Oct 2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Research. 13 (10): 2265–2270. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
Wiemann S, Arlt D, Huber W, Wellenreuther R, Schleeger S, Mehrle A, Bechtel S, Sauermann M, Korf U, Pepperkok R, Sültmann H, Poustka A (Oct 2004). "From ORFeome to biology: a functional genomics pipeline". Genome Research. 14 (10B): 2136–2144. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
Mehrle A, Rosenfelder H, Schupp I, del Val C, Arlt D, Hahne F, Bechtel S, Simpson J, Hofmann O, Hide W, Glatting KH, Huber W, Pepperkok R, Poustka A, Wiemann S (Jan 2006). "The LIFEdb database in 2006". Nucleic Acids Research. 34 (Database issue): D415–D418. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
Zhang JK, Zhao LF, Cheng J, Guo J, Wang DQ, Hong Y, Mao Y (Mar 2007). "Screening and cloning for proteins transactivated by the PS1TP5 protein of hepatitis B virus: a suppression subtractive hybridization study". World Journal of Gastroenterology. 13 (10): 1602–7. doi:10.3748/wjg.v13.i10.1602. PMC 4146906. PMID 17461456.

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This page was last edited on 6 September 2023, at 02:41

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References

External links

Further reading