To install click the Add extension button. That's it.

The source code for the WIKI 2 extension is being checked by specialists of the Mozilla Foundation, Google, and Apple. You could also do it yourself at any point in time.

How to transfigure the Wikipedia

Would you like Wikipedia to always look as professional and up-to-date? We have created a browser extension. It will enhance any encyclopedic page you visit with the magic of the WIKI 2 technology.

Try it — you can delete it anytime.

Install in 5 seconds
4,5
Kelly Slayton
Congratulations on this excellent venture… what a great idea!
Alexander Grigorievskiy
I use WIKI 2 every day and almost forgot how the original Wikipedia looks like.
Live Statistics
English Articles
Improved in 24 Hours
Added in 24 Hours
Languages
Recent
Show all languages
What we do. Every page goes through several hundred of perfecting techniques; in live mode. Quite the same Wikipedia. Just better.
Great Wikipedia has got greater.
.
Leo
Newton
Brights
Milds

Autoimmune progesterone dermatitis

From Wikipedia, the free encyclopedia

Autoimmune progesterone dermatitis
Other namesAPD, Autoimmune progesterone urticaria, Progesterone dermatitis.[1]
SpecialtyDermatology

Autoimmune progesterone dermatitis (APD) occurs during the luteal phase of a woman's menstrual cycle and is an uncommon cyclic premenstrual reaction to progesterone. It can present itself in several ways, including eczema, erythema multiforme, urticaria, angioedema, and progesterone-induced anaphylaxis.[2] The first case of autoimmune progesterone dermatitis was identified in 1964.[3] Reproductive function may be impacted by APD.[4]

YouTube Encyclopedic

  • 1/3
    Views:
    4 236
    868 335
    1 836
  • Dermatite autoimmune da progesterone
  • 7 of the Strangest Allergies
  • PMDD Progesterone Sensitivity and me

Transcription

Signs and symptoms

Skin lesions can present as purpura,[5] urticaria, erythema multiforme, folliculitis, eczema, papulovesicular eruptions, fixed drug eruptions,[6] or vulvovaginal pruritus.[7] There are also reports of anaphylaxis.[8] Symptoms start to show up three to ten days before the onset of menstruation.[9] APD may affect fertility.[4]

Mechanism

It is unknown exactly what causes APD. The use of exogenous progesterones (OCPs) at the beginning of a patient's treatment may increase the possibility that the antigen will be absorbed by antigen-presenting cells and presented to TH2 cells, which may lead to the subsequent synthesis of IgE. However, this mechanism would not account for the pathogenesis in patients whose APD began before this treatment.[9] Although not all studies have shown it, some authors have proposed that hydrocortisone[10] or 17-α-hydroxyprogesterone may cause initial sensitization due to their cross-sensitivity with progesterone.[11]

Diagnosis

An intradermal progesterone injection test is performed in conjunction with a clinical history to confirm the diagnosis of APD.[12]

A delayed or immediate hypersensitivity reaction could be the cause of APD. As a result, intradermal testing might not show a positive result for 24 to 48 hours.[13] Furthermore, progesterone patch testing has been recommended by some authors to further assess for a hypersensitivity reaction.[14] Notably, certain individuals with typical clinical symptoms of APD who improved after treatment for the disorder did not test negative for intradermal growth factors.[15]

See also

References

  1. ^ "Monarch Initiative". Monarch Initiative. Retrieved December 23, 2023.
  2. ^ Prieto-Garcia, Alicia; Sloane, David E.; Gargiulo, Antonio R.; Feldweg, Anna M.; Castells, Mariana (2011). "Autoimmune progesterone dermatitis: clinical presentation and management with progesterone desensitization for successful in vitro fertilization". Fertility and Sterility. Elsevier BV. 95 (3): 1121.e9–1121.e13. doi:10.1016/j.fertnstert.2010.10.038. ISSN 0015-0282. PMID 21092951.
  3. ^ Shelley, Walter B; Preucel, Robert W.; Spoont, Stanley S. (October 5, 1964). "Autoimmune Progesterone Dermatitis". JAMA. American Medical Association (AMA). 190 (1). doi:10.1001/jama.1964.03070140041004. ISSN 0098-7484.
  4. ^ a b Kuruvilla, Merin; Vanijcharoenkarn, Kristine; Wan, Justin; Pereira, Nigel; Chung, Pak (2018). "Exogenous progesterone hypersensitivity associated with recurrent pregnancy loss". The Journal of Allergy and Clinical Immunology: In Practice. Elsevier BV. 6 (4): 1412–1413. doi:10.1016/j.jaip.2017.11.041. ISSN 2213-2198. PMID 29339132. S2CID 42650500.
  5. ^ Wintzen, M.; Goor-van Egmond, M. B. T.; Noz, K. C. (2004). "Autoimmune progesterone dermatitis presenting with purpura and petechiae". Clinical and Experimental Dermatology. Oxford University Press (OUP). 29 (3): 316. doi:10.1111/j.1365-2230.2004.01516.x. ISSN 0307-6938. PMID 15115523. S2CID 26356147.
  6. ^ ASAI, Jun; KATOH, Norito; NAKANO, Mayu; WADA, Makoto; KISHIMOTO, Saburo (November 26, 2009). "Case of autoimmune progesterone dermatitis presenting as fixed drug eruption". The Journal of Dermatology. Wiley. 36 (12): 643–645. doi:10.1111/j.1346-8138.2009.00723.x. ISSN 0385-2407. PMID 19958448. S2CID 39416529.
  7. ^ Banerjee, A K; de Chazal, R (August 1, 2006). "Chronic vulvovaginal pruritus treated successfully with GnRH analogue". Postgraduate Medical Journal. Oxford University Press (OUP). 82 (970): e22. doi:10.1136/pgmj.2005.043950. ISSN 0032-5473. PMC 2585717. PMID 16891434.
  8. ^ Snyder, Joy L.; Krishnaswamy, Guha (2003). "Autoimmune progesterone dermatitis and its manifestation as anaphylaxis: a case report and literature review". Annals of Allergy, Asthma & Immunology. Elsevier BV. 90 (5): 469–477. doi:10.1016/s1081-1206(10)61838-8. ISSN 1081-1206. PMID 12775127.
  9. ^ a b Baptist, Alan P; Baldwin, James L (2004). "Autoimmune progesterone dermatitis in a patient with endometriosis: case report and review of the literature". Clinical and Molecular Allergy. Springer Science and Business Media LLC. 2 (1): 10. doi:10.1186/1476-7961-2-10. ISSN 1476-7961. PMC 509283. PMID 15287986.
  10. ^ Schoenmakers, A.; Vermorkkn, A.; Degreef, H.; Dooms-Goossens, A. (1992). "Corticosteroid or steroid allergy?". Contact Dermatitis. Wiley. 26 (3): 159–162. doi:10.1111/j.1600-0536.1992.tb00286.x. ISSN 0105-1873. PMID 1505180. S2CID 43398231.
  11. ^ Wilkinson, S. M.; Beck, M. H. (1994). "The significance of positive patch tests to 17-hydroxyprogesterone". Contact Dermatitis. Wiley. 30 (5): 302–303. doi:10.1111/j.1600-0536.1994.tb00606.x. ISSN 0105-1873. PMID 8088149. S2CID 5939298.
  12. ^ Nguyen, Tegan; Razzaque Ahmed, A. (2016). "Autoimmune progesterone dermatitis: Update and insights". Autoimmunity Reviews. Elsevier BV. 15 (2): 191–197. doi:10.1016/j.autrev.2015.11.003. ISSN 1568-9972. PMID 26554933.
  13. ^ Hart, Roland (April 1977). "Autoimmune progesterone dermatitis". Archives of Dermatology. 133 (4): 426–430. doi:10.1001/archderm.1977.01640040034003. PMID 192155.
  14. ^ Halevy, Sima; Cohen, Arnon D; Lunenfeld, Eitan; Grossman, Nili (August 2002). "Autoimmune progesterone dermatitis manifested as erythema annulare centrifugum: Confirmation of progesterone sensitivity by in vitro interferon-gamma release". Academy of Dermatology. 47 (2): 311–313. PMID 12140482.
  15. ^ Shelley, Walter B; Preucel, Robert W; Spoont, Stanley S (October 5, 1964). "Autoimmune Progesterone Dermatitis Cure by Oophorectomy". JAMA. 190 (1): 35–38. doi:10.1001/jama.1964.03070140041004. PMID 14197141.

Further reading

External links

This page was last edited on 6 January 2024, at 20:41
Basis of this page is in Wikipedia. Text is available under the CC BY-SA 3.0 Unported License. Non-text media are available under their specified licenses. Wikipedia® is a registered trademark of the Wikimedia Foundation, Inc. WIKI 2 is an independent company and has no affiliation with Wikimedia Foundation.
Contact WIKI 2
Introduction
Terms of Service
Privacy Policy