Armadillo repeat containing 12

ARMC12

Identifiers

ARMC12, C6orf81, armadillo repeat containing 12

External IDs

MGI: 1914895 HomoloGene: 12168 GeneCards: ARMC12

Gene location (Human)

Chr.	Chromosome 6 (human)^[1]

Band	6p21.31	Start	35,737,032 bp^[1]
Band	6p21.31	End	35,749,079 bp^[1]

Gene location (Mouse)

Chr.	Chromosome 17 (mouse)^[2]

Band	17\|17 A3.3	Start	28,749,780 bp^[2]
Band	17\|17 A3.3	End	28,758,084 bp^[2]

RNA expression pattern

Bgee

Human

Mouse (ortholog)

Top expressed in

anterior pituitary

sperm

right lobe of liver

left uterine tube

right adrenal gland

right lobe of thyroid gland

left lobe of thyroid gland

nucleus accumbens

gastric mucosa

putamen

Top expressed in

seminiferous tubule

spermatid

spermatocyte

morula

secondary oocyte

yolk sac

proximal tubule

superior frontal gyrus

cerebellar cortex

kidney

More reference expression data

BioGPS

n/a

Orthologs

Species

Human

Mouse

Entrez


221481


67645

Ensembl


ENSG00000157343


ENSMUSG00000024223

UniProt


Q5T9G4


Q80X86

RefSeq (mRNA)


NM_001286574 NM_001286576 NM_145028


NM_026290

RefSeq (protein)


NP_001273503 NP_001273505 NP_659465


NP_080566

Location (UCSC)

Chr 6: 35.74 – 35.75 Mb

Chr 17: 28.75 – 28.76 Mb

PubMed search

^[3]

^[4]

Wikidata

View/Edit Human

View/Edit Mouse

Armadillo repeat containing 12 is a protein that in humans is encoded by the ARMC12 gene^[5] that plays a crucial role in tumor progression. It is associated with the development of neuroblastoma (NB) as it encourages the growth and aggressiveness of NB cell lines.^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000157343 - Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000024223 - Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: Armadillo repeat containing 12". Retrieved 2017-12-22.
^ Li D, Song H, Mei H, Fang E, Wang X, Yang F, Li H, Chen Y, Huang K, Zheng L, Tong Q (July 2018). "Armadillo repeat containing 12 promotes neuroblastoma progression through interaction with retinoblastoma binding protein 4". Nature Communications. 9 (1): 2829. Bibcode:2018NatCo...9.2829L. doi:10.1038/s41467-018-05286-2. PMC 6053364. PMID 30026490.

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This page was last edited on 6 February 2024, at 22:42

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References