In molecular biology, olfactory marker protein is a protein involved in signal transduction. It is a highly expressed, cytoplasmic protein found in mature olfactory sensory receptor neurons of all vertebrates. OMP is a modulator of the olfactory signal transduction cascade. The crystal structure of OMP reveals a beta sandwich consisting of eight strands in two sheets with a jelly-roll topology.[1] Three highly conserved regions have been identified as possible protein–protein interaction sites in OMP, indicating a possible role for OMP in modulating such interactions, thereby acting as a molecular switch.[2]
YouTube Encyclopedic
-
1/3Views:3 764378 080537 422
-
Satyajit Mayor (NCBS) Part 2: Looking for Functional Rafts in Cell Membranes
-
Autonomic nervous system | Organ Systems | MCAT | Khan Academy
-
Parasympathetic Nervous System: Crash Course A&P #15
Transcription
External links
- Olfactory+marker+protein at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
References
- ^ Baldisseri DM, Margolis JW, Weber DJ, Koo JH, Margolis FL (June 2002). "Olfactory marker protein (OMP) exhibits a beta-clam fold in solution: implications for target peptide interaction and olfactory signal transduction". J. Mol. Biol. 319 (3): 823–37. doi:10.1016/S0022-2836(02)00282-6. PMID 12054873.
- ^ Smith PC, Firestein S, Hunt JF (June 2002). "The crystal structure of the olfactory marker protein at 2.3 A resolution". J. Mol. Biol. 319 (3): 807–21. doi:10.1016/S0022-2836(02)00242-5. PMID 12054872.
 | This article on a gene on human chromosome 11 is a stub. You can help Wikipedia by expanding it. |
This page was last edited on 7 December 2020, at 12:25