To install click the Add extension button. That's it.

The source code for the WIKI 2 extension is being checked by specialists of the Mozilla Foundation, Google, and Apple. You could also do it yourself at any point in time.

How to transfigure the Wikipedia

Would you like Wikipedia to always look as professional and up-to-date? We have created a browser extension. It will enhance any encyclopedic page you visit with the magic of the WIKI 2 technology.

Try it — you can delete it anytime.

Install in 5 seconds
4,5
Kelly Slayton
Congratulations on this excellent venture… what a great idea!
Alexander Grigorievskiy
I use WIKI 2 every day and almost forgot how the original Wikipedia looks like.
Live Statistics
English Articles
Improved in 24 Hours
Added in 24 Hours
What we do. Every page goes through several hundred of perfecting techniques; in live mode. Quite the same Wikipedia. Just better.
Great Wikipedia has got greater.
.
Leo
Newton
Brights
Milds

Desmethylchlorotrianisene

From Wikipedia, the free encyclopedia

Desmethylchlorotrianisene
Clinical data
Other namesDMCTA
Drug classNonsteroidal estrogen
Identifiers
  • (EZ)-4-[2-Chloro-1,2-bis(4-hydroxyphenyl)ethenyl]phenol
PubChem CID
ChemSpider
ChEMBL
Chemical and physical data
FormulaC20H15ClO3
Molar mass338.79 g·mol−1
3D model (JSmol)
  • OC1=CC=C(/C(C2=CC=C(OC)C=C2)=C(Cl)/C3=CC=C(OC)C=C3)C=C1
  • InChI=1S/C20H15ClO3/c21-20(15-5-11-18(24)12-6-15)19(13-1-7-16(22)8-2-13)14-3-9-17(23)10-4-14/h1-12,22-24H
  • Key:XQRLRQNJWROVPF-UHFFFAOYSA-N

Desmethylchlorotrianisene (DMCTA) is a nonsteroidal estrogen which is thought to be the major active metabolite of chlorotrianisene (CTA; TACE).[1][2] It is a 1:1 mixture of cis and trans isomers.[1][2] DMCTA is produced from CTA via mono-O-demethylation catalyzed by cytochrome P450 enzymes in the liver.[1][2] CTA is thought to act as a long-lasting prodrug of DMCTA.[1]

References

  1. ^ a b c d Ruenitz PC, Toledo MM (August 1981). "Chemical and biochemical characteristics of O-demethylation of chlorotrianisene in the rat". Biochem. Pharmacol. 30 (16): 2203–7. doi:10.1016/0006-2952(81)90088-5. PMID 7295335.
  2. ^ a b c Virgil Craig Jordan (1986). Estrogen/antiestrogen Action and Breast Cancer Therapy. Univ of Wisconsin Press. p. 212. ISBN 978-0-299-10480-1.



Stub icon

This drug article relating to the genito-urinary system is a stub. You can help Wikipedia by expanding it.

This page was last edited on 3 December 2022, at 23:21
Basis of this page is in Wikipedia. Text is available under the CC BY-SA 3.0 Unported License. Non-text media are available under their specified licenses. Wikipedia® is a registered trademark of the Wikimedia Foundation, Inc. WIKI 2 is an independent company and has no affiliation with Wikimedia Foundation.
Contact WIKI 2
Introduction
Terms of Service
Privacy Policy