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Cloranolol

From Wikipedia, the free encyclopedia

Cloranolol
Names
IUPAC name
(RS)-1-(tert-butylamino)-3-(2,5-dichlorophenoxy)propan-2-ol
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
KEGG
UNII
  • InChI=1/C13H19Cl2NO2/c1-13(2,3)16-7-10(17)8-18-12-6-9(14)4-5-11(12)15/h4-6,10,16-17H,7-8H2,1-3H3
    Key: XYCMOTOFHFTUIU-UHFFFAOYAX
  • Clc1ccc(Cl)cc1OCC(O)CNC(C)(C)C
Properties
C13H19Cl2NO2
Molar mass 292.20 g·mol−1
Pharmacology
C07AA27 (WHO)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Cloranolol (Tobanum) is a beta blocker.[1]

Synthesis

β-Adrenergic blocker. Prepn:[2]

References

  1. ^ Kulcsár-Gergely J. (July 1989). "Action of beta-adrenoceptor blockers on liver function of rats". Arzneimittelforschung. 39: 782–5. PMID 2571334.
  2. ^ G. Richter, DE 2213044, "Racemisches und optisch aktives 1-(2,5-Dichlorphenoxy)-3-tert.butylamino-2-propanol und ihre Salze, sowie ihre Verwendung und Verfahren zu deren Herstellung derselben [Racemic and optically active 1-(2,5-dichlorophenoxy)-3-tertbutylamino-2-propanols and their salts, as well as their use and process for their preparation]", published 1972-09-28, assigned to Richter Gedeon Vegyeszeti Gyar R.T. .


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This page was last edited on 16 February 2022, at 15:38
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